Introduction: Obsessive-Compulsive Disorder (OCD) is a disabling mental condition that its proteomic profiling is not yet investigated. Proteomics is a valuable tool to discover biomarker approaches. It can be helpful to detect protein expression changes in complex disorders such as OCD. Methods: Here, by the application of 2D gel electrophoresis (2DE), a pilot study of serum proteome profile ...

Most economists are not familiar with so-called biomarker data. We attempt here to provide an introduction to such data and to describe the econometric structure of simple biomarker equations. We draw upon information on the heart rate, systolic and diastolic blood pressure, fibrinogen, and C-reactive protein levels of 100,000 adults. We show that it is extremely important to control for fruit ...

cerebrovascular accidents rank first in the frequency and importance among all neurological disease. although a number of studies had shown increased level of the high sensitive c-reactive protein (hs-crp) in patients with ischemic stroke, the association of increased hs-crp with various type of stroke especially the assessment hs-crp level in ischemic and hemorrhagic stroke have not been inves...

conclusions molecular assays in the early stages of the disease could help in elucidating the effectiveness of the mbp as a prognostic factor in ms. methods this study is convergence of three arms including in silico and in vitro (bioinformatics) with the in vivo (experimental). a novel methodology combining molecular techniques was used to confirm the antigenic properties of mbp and study its ...

Today's proteomic analyses are generating increasing numbers of biomarkers, making it essential to possess highly specific probes able to recognize those targets. Antibodies are considered to be the first choice as molecular recognition units due to their target specificity and affinity, which make them excellent probes in biosensor development. However several problems such as difficult direct...

exposure to toluene can be associate with genotoxicity, neurological dysfunction, reproductive toxicity, and etc. biomonitoring of hippuric acid (ha) is used for a long time as an occupational exposure index to toluene. the aim of this study was to explore efficiency of ha as a biomarker of exposure to low level of toluene for iranian petroleum depot workers in 2011. personal monitoring to tolu...

copper is a very common element in water resources. for this reason, concerns about the risks and consequences of this element in water contamination are arising. the purpose of this study was to investigate the effects of water-born cuo (copper (ii) oxide) on the rainbow trout, oncorhynchus mykiss gill tissue to establish a suitable biomarker for copper in water resources. samples with 18±3g b...