نتایج جستجو برای: protein binding

تعداد نتایج: 1446869  

Journal: :RSC medicinal chemistry 2023

Binding configuration of a de novo stapled peptide on SARS-CoV-2 spike protein, as predicted by molecular simulation. Stapled residues enhance stability while interacting engage key amino acids the protein receptor-binding domain.

Journal: :applied biotechnology reports 0
mohammad ali arefpour torabi biology research center, faculty and institute of basic science, imam hossein university, tehran, iran gholam reza olad applied biotechnology research center, baqiyatallah university of medical sciences, teh-ran, iran shahram nazarian biology research center, faculty and institute of basic science, imam hossein university, tehran, iran jafar salimian chemical injury research center, baqiyatallah university of medical sciences, teh-ran, iran samaneh khodi applied biotechnology research center, baqiyatallah university of medical sciences, teh-ran, iran mohamad javad bagheripour biology research center, faculty and institute of basic science, imam hossein university, tehran, iran

diphtheria is a fatal disease caused by exotoxin of corynebacterium     diphtheria .  this toxin consists of   two chains, catalytic chain (a) and binding (b) chain. by binding chain (b),   the toxin binds to its receptor on numerous body cells such as myocardial,   kidney and peripheral nerve cells. after entering, catalytic chain (a)   inhibits protein synthesis and finally can cause cell dea...

F. Attar, S. Khavari-Nejad

In the near future, design of a new generation of drugs targeting proteins will be required. Considering the complex bond between the drug and protein, the structure and stability of the target protein should be considered. So far, a series of in vitro investigations have been conducted with the aim of predicting drug-biological medium interactions. In these studies, use of spectroscopic method...

Azad M, Sabbaghian M Shahhosseini M

Background: Septins are members of highly conserved polymerizing GTP binding proteins well described in the animal kingdom. 14 Septin proteins have been characterized in humans (SEPT1-SEPT14), some of which are tissue-specific. All of 14 genome-mapped human septins contain a highly conserved central GTP-binding domain which is very critical in GTPase signaling properties as well as oligomerizat...

Journal: :iranian journal of science and technology (sciences) 2004
b. haghighi

interaction of glucose 6-phosphate dehydrogenase from s. aureofaciens with nad+, nadp+and glucose 6-phosphate were investigated using different fluorescent probes. binding of nad+, nadp+and s-nadph to the native enzyme quenched intrinsic protein fluorescence by 100%, 10% and 21%,respectively, from which kd values of nad+ (6.5 mm), nadp+ (92.0 μm) and s-nadph (122.0 μm)were calculated. binding o...

Journal: :physical chemistry research 2015
maliheh sadat atri ali akbar saboury faizan ahmad

most of the biological phenomena are influenced by intermolecular recognition and interaction. thus, understanding the thermodynamics of biomacromolecule ligand interaction is a very interesting area in biochemistry and biotechnology. one of the most powerful techniques to obtain precise information about the energetics of (bio) molecules binding to other biological macromolecules is isothermal...

Journal: :iranian journal of applied animal science 2015
k.f. mahrous m.s. hassanane m. abdel mordy h.i. shafey h.e. rushdi

the genetic polymorphism of some genes related to meat production in three egyptian sheep breeds (barki, rahmani and osseimi) was studied. the candidate genes were: calpastatin, myostatin, diacylglycerol-acyltransferase1, insulin-like growth factor binding protein-3 and booroola fecundity gene. the technique applied was the restriction fragment length polymorphism for the polymerase chain react...

Lactoferrin (Lf) is an iron-binding multi-functional glycoprotein which has numerous physiological functions such as iron transportation, anti-microbial activity and immune response. In this study, different in silico approaches were exploited to investigate Lf protein properties in a number of mammalian species. Results showed that the iron-binding site, DNA and RNA-binding sites, signal pepti...

Mahnam, Karim, Mirahmadi Babaheidari, Fatemeh,

The XIAP protein is a member of apoptosis proteins family. The XIAP protein plays a central role in the inhibition of apoptosis and consists of three Baculoviral IAP Repeat domains. The BIR3 domain binds directly to the N-terminal of caspase-9 and therefore it inhibits apoptosis. N-terminal tetrapeptide region of SMAC protein can bind to BIR3, inhibit it and subsequently induce apoptosis. In th...

The histone-like protein HU is the most-abundant DNA-binding protein in bacteria. The HU protein non-specifically binds and bends DNA as a hetero- or homodimer, and can participate in DNA supercoiling and DNA condensation. It also takes part in DNA functions such as replication, recombination, and repair. HU does not recognize any specific sequences but shows a certain degree of specificity to ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید