background: the extremely low-frequency electromagnetic field (elf-emf), mainly emitted by electric transmission lines and household electronic appliances, is becoming a worldwide health risk. it is imperative to investigate the biological impacts of elf-emf and to identify products that are resistant to the radiation from 50 hz elf-emf. in this study, we investigated the biological impacts of ...

background and objectives: alzheimer's disease (ad) as a neurodegenerative disorder is the most common form of dementia in the elderly. according to the amyloid hypothesis, accumulation of amyloid beta (aβ) plaques, which are mostly constituted of aβ peptide aggregates, triggers pathological cascades that lead to neuronal cell death. thus, modulation of aβ toxicity is the hopeful therapeut...

alzheimer’s disease (ad) is a neurodegenerative disease that was characterized with deposit of beta amyloid (aβ) aggregate in senile plaque. oxidative damage to neurons and loss of cholinergic neurons in forebrain region are observed in this disease. melissa officinalis is a medicinal plant from lamiaceae family, used traditionally in the treatment of cognitive disorders. it has cholinomimetic ...

Hydrogen sulfide (H2S), a traditionally known toxic gas, is now recognized as a third gasotransmitter and exerts protective effects against various system diseases and cellular injuries. This article put emphasis on the protective effects of H2S on gastric injury and the well-known signaling mechanisms underlying these protective effects, based on existing literature. H2S, either endogenous or ...

edaravone, an antioxidant and radical scavenger, showed protective effects against oxidative stress-like condition. paraquat (pq) is a toxic herbicide considerable evidence suggests that oxidative stress and mitochondrial dysfunction contribute to pq toxicity. in this study, protective effect of edaravone against pq induced toxicity and reactive oxygen species (ros) generation in a549 cells and...