Background: Some ssues in human body are radiobiologically different from water and these inhomogeneity must be considered in dose calcula on in order to achieve an accurate dose delivery. Dose verifica on in complex radia on therapy techniques, such as intensity‐modulated radia on therapy (IMRT) calls for volumetric, ssue equivalent and energy independent dosimeter. The purpose of this study i...

BACKGROUND Low-risk prostate cancer (PCa) patients have excellent outcomes, with treatment modality often selected by perceived effects on quality of life. Acute urinary symptoms are common during external beam radiotherapy (EBRT), while chronic symptoms have been linked to urethral dose. Since most low-risk PCa occurs in the peripheral zone (PZ), we hypothesized that EBRT using urethral sparin...

The aim of this study was to investigate the clinical significance effect age on disease control in men who received high-dose intensity-modulated radiation therapy (IMRT) for nonmetastatic prostate cancer (NMPCa). NMPCa patients with favorable intermediate very high-risk features (National Comprehensive Cancer Network risk classification) treated IMRT at our institution between September 2000 ...

PURPOSE To study the feasibility of unified intensity-modulated arc therapy (UIMAT) which combines intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) optimization and delivery to produce superior radiation treatment plans, both in terms of dose distribution and efficiency of beam delivery when compared with either VMAT or IMRT alone. METHODS An inverse plannin...

AIM The aim of our study was the dosimetric and physical evaluation of the CK and IMRT treatment plans for 16 patients with localized prostate cancer. BACKGROUND Intensity modulated radiation therapy (IMRT) is one of the recent technical advances in radiotherapy. The prostate is a well suited site to be treated with IMRT. The challenge of accurately delivering the IMRT needs to be supported b...

BACKGROUND AND PURPOSE The scattered radiation from the treatment volume might be more significant for children than for adults and, as a consequence, modern radiotherapy treatment techniques such as IMRT and passive proton therapy could potentially increase the number of secondary cancers. In this report, secondary cancer risk resulting from new treatment technologies was estimated for an adul...

BACKGROUND Image-guidance systems allow accurate interfractional repositioning of IMRT treatments, however, these may require up to 15 minutes. Therefore intrafraction motion might have an impact on treatment precision. 3D geometric data regarding intrafraction prostate motion are rare; we therefore assessed its magnitude with pre- and post-treatment fiducial-based imaging with cone-beam-CT (CB...

We use a rectal balloon for prostate immobilization during intensity modulated radiotherapy (IMRT) prostate treatment. To improve the accuracy of our prostate planning target volume, we have measured prostate displacements using computed tomography (CT)-CT fusion on patients that previously received gold seed implants. The study consists of ten patients that were scanned twice per week during t...

Accuracy and precision of leaf positioning in multileaf collimators (MLCs) are significant factors for the accuracy of IMRT treatments. This study aimed to inves-tigate the accuracy and repeatability of the MLC leaf positioning via the DAVID invivo dosimetric system for dynamic and static MLC systems. The DAVID system was designed as multiwire transmission ionization chamber which is placed in ...

Introduction: Electronic portal imaging devices (EPIDs) are extensively used for dosimetric information of pre-treatment field verification and in-vivo dosimetry for Intensity Modulated Radiotherapy (IMRT). In the present work, we have implemented the newly developed portal dosimetry software using independent dose prediction algorithm EPIDose and evaluated this new tool for the pretreatment IM...