• The use of immunohistochemistry for basal cell markers and AMACR for the diagnosis of limited adenocarcinoma of the prostate should be used as an adjunct to the H&E diagnosis as there is false positive and negative staining with these markers. • Examples of labeling of prostate adenocarcinoma with basal cell markers include: aberrant scattered HMWCK staining of cancer cells; rarely the retent...

The mRNA for Rvp.1 (rat ventral prostate) increases in abundance before gland involution after androgen deprivation. Rvp.1 is homologous to CPE-R, the high-affinity intestinal epithelial receptor for Clostridium perfringens enterotoxin (CPE), and is sufficient to mediate CPE binding and trigger subsequent toxin-mediated cytolysis. Rvp.1 (claudin-3) and CPE-R (claudin-4) are members of a larger ...

The mRNA for Rvp.1 (rat ventral prostate) increases in abundance before gland involution after androgen deprivation. Rvp.1 is homologous to CPE-R, the high-affinity intestinal epithelial receptor for Clostridium perfringens enterotoxin (CPE), and is sufficient to mediate CPE binding and trigger subsequent toxin-mediated cytolysis. Rvp.1 (claudin-3) and CPE-R (claudin-4) are members of a larger ...

INTRODUCTION Prostate cancer has a high tendency to spread to bone. Pulmonary metastasis and generalized lymphadenopathy commonly develop after pelvic and bone involvement have already occurred. Few patients with prostate cancer present initially with symptomatic metastatic lung lesions and lymphadenopathy without any other concomitant distant dissemination. CASE PRESENTATION We report a case...

BACKGROUND The relationship between sex hormone-related treatment for prostate cancer and the risk of colorectal cancer is controversial. METHODS A prostate cancer cohort was initiated from the Swedish Cancer Registry of patients diagnosed between 1961 and 2008. Patients diagnosed with prostate cancer between 1961 and 1980 were generally treated with estrogen. The cohort diagnosed between 198...

Chronic inflammation has been considered an important risk factor for development of prostate cancer. Toll-like receptors (TLRs) recognize microbial moieties or endogenous molecules and play an important role in the triggering and promotion of inflammation. In this study, we examined whether expression of TLR4 and TLR5 was associated with progression of prostate transformation in the transgenic...

INTRODUCTION Ductal adenocarcinoma is a rare variety of the common acinar adenocarcinoma. It usually presents with refractory symptoms, and during cystoscopy, it is seen as an exophytic lesion at the area of the verumontanum. CASE PRESENTATION An 82-year-old Caucasian man was diagnosed with ductal adenocarcinoma of the prostate after undergoing transurethral resection of the prostate for urin...

Case 1. A 60-year-old man was treated with 72 Gy. external beam radiation therapy for Gleason score 4 3 adenocarcinoma of the prostate diagnosed by transrectal ultrasound guided biopsy. After treatment prostate speci c antigen (PSA) decreased to 1.3 ng./ml. One year later PSA had increased to 2.0 ng./ml. Transrectal ultrasound guided biopsy revealed recurrent prostatic adenocarcinoma. Salvage c...

Abstract Background Primary signet-ring cell carcinoma (SRCC) of the prostate is a rare and aggressive subtype adenocarcinoma with poor prognosis, only approximately 60 cases reported worldwide. Case presentation A 62-year-old man presented acute urinary retention hematuria, after year’s history lower tract symptoms. Digital rectal examination revealed an irregular hard prostate. Flexible cysto...