BACKGROUND We are the first to evaluate the prevalence of renal artery stenosis (RAS) in consecutive patients with acute myocardial infarction (AMI) referred for primary percutaneous coronary intervention from a single tertiary center. As a novelty, we assessed hydration and metabolic status and measured arterial stiffness. We elaborated a predicting model for RAS in AMI. METHODS AND RESULTS ...

Glycoprotein IIb/IIIa antagonists are well established for their effectiveness in improving clinical outcomes in acute coronary syndrome patients undergoing percutaneous coronary intervention. Acute profound thrombocytopenia is a rare complication of abciximab. We present a case which was managed successfully for the rare complication of acute profound thrombocytopenia after using abciximab and...

BACKGROUND Microvascular perfusion is often impaired after primary percutaneous coronary intervention (PCI). We proposed that in situ thrombosis might contribute to poor myocardial perfusion in this setting. To test this hypothesis, we evaluated the effect of low-dose intracoronary streptokinase administered immediately after primary PCI. METHODS Forty-one patients undergoing primary PCI were...

REPERFUSION THERAPY WITH THROMBOLYSIS OR PRImary percutaneous coronary intervention (PCI) has been a major advance in the treatment of acute ST-segment elevation myocardial infarction (MI), with a 25% reduction in mortality with thrombolysis. Primary PCI has been considered in the American College of Cardiology/American Heart Association (ACC/AHA) guidelines in 1999 to be an alternative to thro...

BACKGROUND Although some studies have shown potential benefit for ischemic postconditioning (IPoC) during primary percutaneous coronary intervention (PCI) in improving surrogate markers of reperfusion and infarction size, the benefit of this approach on clinical outcomes remains unknown. METHODS AND RESULTS Electronic databases were searched for randomized clinical trials that compared IPoC v...

BACKGROUND Primary percutaneous coronary intervention (PCI) is at present the most effective procedure for reducing the mortality rate of patients with acute myocardial infarction (AMI). However, there is a great difference between Japan and other countries in the rate of primary PCI. METHODS AND RESULTS Registration period, number of patients with AMI, rates of primary PCI or thrombolysis an...

Background:Little is known about the effect of coronavirus disease 2019 (COVID-19) pandemic and outbreak response measures on door-to-balloon time (D2B). This study examined both D2B clinical outcomes patients with STEMI undergoing primary percutaneous coronary intervention (PPCI).

BACKGROUND Current guidelines recommend abciximab as the preferred agent for patients undergoing primary percutaneous coronary intervention, yet small-molecule glycoprotein IIb/IIIa inhibitors are more commonly used in clinical practice. The objective of our meta-analysis was to evaluate for differences in clinical outcome between small-molecule glycoprotein IIb/IIIa inhibitors and abciximab in...

BACKGROUND Prior studies have suggested that blacks with acute ST-segment-elevation myocardial infarction have increased bleeding risks with fibrinolysis relative to whites, yet these data were quite limited. Additionally, it is unknown whether there are racial differences in bleeding risks among patients with ST-segment-elevation myocardial infarction receiving primary percutaneous coronary in...