PURPOSE In epilepsy, many studies were focus on apoE gene polymorphism and found APOE epsilon4 to be associated with earlier onset of temporal lobe epilepsy. There is not any study about apoE in cerebrospinal fluid (CSF) of epileptic patients, so we detect the CSF-apoE and determine whether it is changed after seizure. METHODS A total of 60 epileptic patients and 28 subjects with no evidence ...

Seizure episode is most common in males than females this study. Among the males, age group of 21-40 years affecting with seizures. Major occurrence seizure when patient awake state. Most around 80% study presented single seizure. Generalized Tonic Clonic form Infection and inflammation were cause Neurocysticercosis under infectious seizure, followed by tuberculomas. Ischemia second Incidence m...

PURPOSE This study was conducted to evaluate the efficacy and safety of anterior corpus callosotomy with a keyhole approach on refractory seizures and to evaluate this procedure for drop attacks (DAs) and generalized tonic-clonic seizures (GTCSs). METHODS All refractory seizure patients underwent anterior corpus callosotomy (n=31) without other epilepsy surgery. Seizure response and procedure...

We investigated the type and frequency of interictal primary headache and peri-ictal headache in 109 patients with partial-onset and 26 patients with generalized onset seizures in this study. Interictal headaches were present in 50 (40.7%) of 135 patients. Comparing the interictal headache on the basis of seizure type, we couldn't find any significant difference between the seizure groups. Seve...

Objective: Antiepileptic drugs (AEDs) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current AEDs therapy. Some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. The aim of the p...

Epilepsy is a chronic disorder characterized by the appearance of frequent seizure episodes associated with diverse group symptoms. Generalized tonic-clonic most common type motor usually impaired awareness or complete loss consciousness. Despite all available medications one third people epilepsy still seems to be severely affected. Management remains challenge medical community. Therapeutic a...

We report the case of a 14-year-old boy with a past history of primary generalized seizures, who had been seizure-free for 2 years on sodium valproate and presented with generalized tonic clonic seizures suggestive of breakthrough seizures. Examination revealed hypertension, impetiginous lesions of the lower limbs, microscopic hematuria, elevated anti-streptolysin O titre and low complement lev...