نتایج جستجو برای: primary bone tumors

تعداد نتایج: 1066082  

2014
Reena Sarkar

Primary bone tumors of the jaw are rare. The neoplastic cells in these tumors are the osteoblasts and osteoclasts. The gnathic bone tumors have also been referred to as borderline. The clinicopathologic approach towards these bony lesions have been reviewed.

Journal: :Journal of Radiation Research and Applied Sciences 2015

2017
Alexandra Gangi

Primary sacral tumors are rare, accounting for approximately 5–7% of all spinal tumors [1]. Metastases are the most common malignant tumors of the sacrum and can be derived from lung, breast, kidney, prostate, head and neck, gastrointestinal, or skin (melanoma) cancers [2, 3, 62]. Primary benign and malignant tumors of the sacrum may arise from bone or neural elements or the bone marrow in case...

Journal: :Romanian Journal of Orthopaedic Surgery and Traumatology 2018

2016

Neuroendocrine tumors are relatively rare tumors with an incidence of 5.25 per 100,000 per year in the United States [1]. They range from well differentiated slow growing tumors to highly aggressive poorly differentiated tumors [2]. The common primary sites of neuroendocrine carcinomas are lung and gastrointestinal tract. However, 3-5 % of these tumors are diagnosed as metastatic disease with u...

Journal: :Orthopedics 2013
Nathan Evaniew Victoria Tan Naveen Parasu Erik Jurriaans Karen Finlay Benjamin Deheshi Michelle Ghert

Benign primary bone tumors are commonly treated with intralesional curettage with or without the use of surgical adjuvants. The reconstructive approach to the resulting contained bone defects is controversial, and clinical practice is varied. Synthetic bone substitutes may provide early mechanical support while minimizing the risks of disease transmission, nonunion, infection, and donor-site mo...

Journal: :Journal of cellular physiology 2011
Daniele Santini Giuseppe Perrone Ilaria Roato Laura Godio Francesco Pantano Donatella Grasso Antonio Russo Bruno Vincenzi Maria Elisabetta Fratto Roberto Sabbatini Chiara Della Pepa Camillo Porta Alessandro Del Conte Gaia Schiavon Alfredo Berruti Rosa Maria Tomasino Mauro Papotti Nicola Papapietro Andrea Onetti Muda Vincenzo Denaro Giuseppe Tonini

Receptor activator of NFκB ligand (RANKL), RANK, and osteoprotegerin (OPG) represent the key regulators of bone metabolism both in normal and pathological conditions, including bone metastases. To our knowledge, no previous studies investigated and compared RANK expression in primary tumors and in bone metastases from the same patient. We retrospectively examined RANK expression by immunohistoc...

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