BACKGROUND AND OBJECTIVE We evaluated the effectiveness, block duration, postanesthesia care unit stay and adverse effects of using intrathecal low dose bupivacaine and fentanyl combination and compared with conventional dose prilocaine and fentanyl combination for day case transurethral resection of prostate surgery in geriatric patient population. MATERIALS AND METHODS Sixty patients were r...

BACKGROUND Our aim was to estimate the ED95 of prilocaine 1% w/v for femoral nerve block. METHODS This two-stage dose-finding sequential clinical trial followed an adaptive design based on the continual reassessment method (CRM). Adult patients undergoing Vastus medialis muscle biopsy under ultrasound-guided femoral nerve block were recruited. Data from previously published studies and our ow...

OBJECTIVE To determine whether the addition of 8 mg dexamethasone to axillary brachial plexus block would prolong the duration of sensory and motor block in patients undergoing hand and forearm surgery. METHODS The prospective, randomised, double-blinded study was conducted at the Eskisehir Osmangazi University Medical School, Turkey, from October 2008 to December 2009. It comprised 45 Americ...

Plasma levels of local anaesthetics following their injection are affected by many factors. Serial plasma levels following injection of lignocaine and prilocaine at various rates in over 500 patients have been measured and this has allowed some of these factors to be assessed and quantified. The vascularity of the site of injection causes major differences in the maximum plasma level. Prilocain...

Introduction. Topical application of local anesthetics is currently considered to be the easiest, most effective, and convenient way for treatment of patients who may be undergoing superficial dermatosurgical procedures. Materials and Methods. This study compares the anesthetic potential of 2.5% lidocaine and 2.5% prilocaine topical cream with 7% lignocaine and 7% tetracaine combination cream f...

Introduction Spinal anaesthesia (SA) is the most commonly used anesthetic technique for transurethral resection of prostate (TURP) surgery in geriatric patient population [1]. Many geriatric patients have coexisting cardiac or pulmonary diseases, so it’s very important to limit the distribution of the block to prevent the possible hemodynamic and pulmonary adverse effects. The purpose of this s...

objective: to compare the efficacy of emla cream and lidocaine injection to reduce pain during episiotomy repair. materials and methods: a total of 46 primiparous women with normal pregnancy who referred for normal vaginal delivery and needed episiotomy repair were selected and randomly divided into two groups. for emla group, one hour before the estimated time of delivery, 5g of emla cream was...

The effects of the cutaneous application of EMLA cream (a eutectic mixture of lignocaine and prilocaine in their base form) were studied in volunteers. When tested by pin-prick, EMLA cream 2.5% and 5% produced analgesia of the area tested, the cream being most effective if left in contact with the skin for 60 min. The pain produced by the insertion of an i.v. cannula was successfully blocked by...

transient neurologic symptoms after intrathecal injection of lidocaine. Anesthesiology 2002; 97: 257±8 7 Sumi M, Sakura S, Kosaka Y. Intrathecal hyperbaric 0.5% tetracaine as possible cause of transient neurological toxicity. Anesth Analg 1996; 82: 1076±7 8 Sakura S, Sumi M, Sakaguchi Y, et al. The addition of phenylephrine contributes to the development of transient neurological symptoms after...