نتایج جستجو برای: prejunctional

تعداد نتایج: 297  

Journal: :American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 1998

Journal: :Circulation research 1983
R A Cohen J T Shepherd P M Vanhoutte

The effects of endogenous and of exogenous norepinephrine were studied in isolated rings of canine left circumflex coronary artery and its first ventricular branch. Norepinephrine was released from adrenergic nerve endings by transmural electrical stimulation and by tyramine. In rings contracted with prostaglandin F2 alpha, transmural electrical stimulation resulted in frequency-dependent relax...

2002
JOHN M. BISHAI LUIT PENNINGA ROEL NIJLAND ROGIER MEULENAAR CIPRIAN P. GHEORGHE YU ZHAO JOHN N. BUCHHOLZ LUBO ZHANG LAWRENCE D. LONGO Roel Nijland Rogier Meulenaar Ciprian P. Gheorghe Yu Zhao John N. Buchholz Lubo Zhang

Bishai, John M., Luit Penninga, Roel Nijland, Rogier Meulenaar, Ciprian P. Gheorghe, Yu Zhao, John N. Buchholz, Lubo Zhang, and Lawrence D. Longo. Preand postjunctional 2-adrenergic receptors in fetal and adult ovine cerebral arteries. Am J Physiol Regulatory Integrative Comp Physiol 282: R1654–R1662, 2002; 10.1152/ajpregu. 00475.2001.—In ovine cerebral arteries, adrenergic-mediated vasoconstri...

Journal: :Hypertension 1987
W B Jeffries L T Tam Y Wang D D Smyth W A Pettinger

Chronic (3-day) treatment with prazosin causes an increase in renal alpha 2-adrenergic receptor density and the relocation of renal tubular alpha 2-adrenergic receptors from extrajunctional to postjunctional sites. We investigated whether chronic prazosin treatment (2 mg/kg, i.p.) caused a functional alteration of other renal alpha 2-adrenergic receptors, using the isolated perfused rat kidney....

Journal: :Circulation 2001
E R Azevedo T Kubo S Mak A Al-Hesayen A Schofield R Allan S Kelly G E Newton J S Floras J D Parker

BACKGROUND Activation of the sympathetic nervous system has important prognostic implications in chronic heart failure. Nonselective versus selective beta-adrenergic receptor antagonists may have differential effects on norepinephrine release from nerve terminals mediated by prejunctional beta(2)-adrenergic receptors. METHODS AND RESULTS Thirty-six patients with chronic heart failure were ran...

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