Purpose: The purpose of this mini review is to elucidate if cervical pessary, with or without progesterone is applicable to twin pregnancies. One-quarter of preterm births (PTB) are twin pregnancies. Cervical cerclage, progesterone, and cervical pessary decrease the PTB incidence in singleton pregnancies. Retrospective cohorts suggest that cervical cerclage is not harmful, and is possibly benef...

OBJECTIVE To examine the effect of the bivalent human papillomavirus (HPV) vaccine on miscarriage. DESIGN Observational long term follow-up of a randomized, double blinded trial combined with an independent unvaccinated population based cohort. SETTING Single center study in Costa Rica. PARTICIPANTS 7466 women in the trial and 2836 women in the unvaccinated cohort enrolled at the end of t...

Objective The purpose of this study was to compare Free Beta-HCG and PAPPA levels in single normal and under IVF pregnancies 11-13w + 6d of gestational age. MaterialsAndMethods In this observational study that was performed as a cohort, 300 consecutive single IVF pregnancies and 700 single normal pregnancies were enrolled about 11-13w + 6d of gestational age and Free Beta-HCG and PAPPA was comp...

BACKGROUND Serum biochemical markers [free betahCG (fbetahCG); pregnancy-associated plasma protein-A (PAPP-A)] used in first trimester Down's syndrome screening have not been fully investigated in pregnancies achieved by assisted reproduction techniques. We present data on pregnancies conceived by all types of assisted reproduction techniques, including pregnancies following ovum donation (OD) ...

In this study we compared the pregnancy outcome of 576 pregnancies after prenatal diagnosis with that of 540 pregnancies without prenatal diagnosis in our microinjection programme. Amniocentesis was suggested for singleton pregnancies (n = 465) and chorionic villus sampling (CVS) was proposed for twin pregnancies (n = 111 pregnancies, 222 fetuses). A total of 365 patients with singleton pregnan...

The purpose of this study is to compare perinatal outcomes of twin pregnancies complicated by gestational diabetes (GDM) with those unaffected by GDM. A total of 1,154 twin pregnancies who delivered at Cheil General Hospital, between January 1998 and December 2002 were recruited to participate in a retrospective analysis. Out of these twin pregnancies, 37 women were had GDM. Four pregnancies ex...

BACKGROUND The aim of this study was to evaluate telomerase activity in tissue from cases of gestational trophoblastic disease (GTD) and in placental tissue from early and late human pregnancies. METHODS We used a telomeric repeat amplification protocol assay to measure telomerase activity in 132 tissue samples from normal early pregnancies, spontaneous abortions, normal late pregnancies, cas...

OBJECTIVE To compare maternal and neonatal outcome of pregnancies achieved by assisted reproduction technique (ART) according to the guidelines of the newly established Italian ART law 40/2004, with that of naturally conceived. DESIGN Three hundred and sixty-four ART pregnancies and 304 naturally conceived pregnancies were analyzed in terms of the incidence of obstetric complications and peri...

UNLABELLED Pregnancy may precipitate acute episodes of thrombotic thrombocytopenic purpura (TTP), but pregnancy outcomes in women who have recovered from acquired TTP are not well documented. We analyzed pregnancy outcomes following recovery from TTP associated with acquired, severe ADAMTS13 deficiency (ADAMTS13 activity <10%) in women enrolled in the Oklahoma TTP-HUS Registry from 1995 to 2012...

The management of pregnant patients with essential thrombocythemia (ET) and polycythemia vera (PV) may be problematic. In the literature there are approximately 300 cases of pregnancies reported in ET and less than 50 pregnancies reported in PV. To reduce the effect of reporting bias, we selected articles with either > 10 pregnancies or at least six patients, and here report on the outcome of 1...