Arsenic trioxide (As₂O₃) is a highly effective treatment for patients with refractory/relapsed acute promyelocytic leukemia (APL), but resistance to As₂O₃ has recently been seen. In the present study, we report the findings that 2 of 15 patients with refractory/relapsed APL treated with As₂O₃ were clinically As₂O₃ resistant. Leukemia cells from these 2 patients harbored missense mutations in pr...

PURPOSE The aim of this study was to investigate the effect of self-paced active recovery (AR) and passive recovery (PR) on blood lactate removal following a 200 m freestyle swimming trial. PATIENTS AND METHODS Fourteen young swimmers (with a training frequency of 6-8 sessions per week) performed two maximal 200 m freestyle trials followed by 15 minutes of different recovery methods, on separ...

Lupinus polyphyllus Lindl is a perennial herbaceous plant widely distributed in the Northeastern states of USA, Canada, Europe, Argentina and New Zealand. This on Kola Peninsula. L. contains alkaloids, main which are lupanine, lupinine, sparteine. The aim study was to determine cytotoxicity aqueous extracts seeds studied their effect biomass growth by Allium-test method. It found that solutions...

Cet article présente les contributions du dossier consacré à l’Amérique latine en replaçant dans le contexte plus large de au xxie siècle. Il propose d’interpréter cette réalité partir trois contradictions liées modèle développement, aux conflits politiques et l’insertion internationale sous-continent. Sont ensui...

Dendrobium nobile Lindl., an epiphytic herb distributed in the Southeast Asia, is used as a tonic and antipyretic herbal medicine in China. In this study, a water-soluble acidic heteropolysaccharide, DNP-W4, containing mannose, glucose, galactose, xylose, rhamnose, and galacturonic acid, in the molar ratios of 1.0:4.9:2.5:0.5:1.0:0.9, was obtained from the stems of Dendrobium nobile Lindl. Usin...

Dans la lutte contre le terrorisme, l’accélération des procédures et modification dispositifs judiciaires donnent une place prépondérante à conception sécuritaire de l’urgence. À travers l’analyse deux recours pour excès pouvoir mesures administratives prises en vue prévenir « atteintes l’ordre public &#187...

Evolutionis crucial inSoftwareProcess Modeling(PM) and tems. EPOSis aPMsupport system, usingthe sameConss Schema (types PM0. Pr ovi de PMSuppor t : pr oces s mode l i ng l anguage , pr oces s t ool s . PM1. El i c i t r equi r ement s f or pr oces s mode l . PM2. Anal ys e/des i gn a templ ate model ( \s ymbol i c pr ogr am") . PM3. Impl ement an enactabl e model ( \l oad i mage") . PM4. Execut...

(a) In this question you are asked to show that randomness extraction is possible only from sources that are statistically close to sources with high min-entropy; thus, high minentropy is both sufficient and necessary for randomness extraction. More formally, let X be any distribution over {0, 1}n and let Ext : {0, 1}n × {0, 1}d → {0, 1}m. Suppose that Ext(X,Ud) is ǫ-close to the uniform distri...

Popul ar myt hs t hat cheaper memor y, hi ghs peed l i nks , and hi ghs peed pr oces s or s wi l l s ol ve t he pr obl emof con i n comput er networ ks ar e s hown t o be f al s e . A s i mpl e de ni t i on f or conges t i on bas ed on s uppl y and dema r es our ce s i s pr opos ed and i s t hen us ed t o c l as s i f y var i ous conges t i on s chemes . The i s s ues t hat make t he pr obl ema...