The aim of this study was to estimate allelic and genotypic frequencies of five DNA markers that are positional and functional candidates for milk production traits in Czech Fleckvieh cattle. In addition, we evaluated the association of these markers with milk production traits and breeding values for milk production traits and also estimated linkage disequilibrium (LD) between two markers with...

Obesity continues increasing at epidemic levels worldwide, as does the number of genetic studies that focus on obesity. Body mass index (BMI) is often used to characterize weight phenotypes and obesity status due to its simplicity. Refined measurements of body composition may be needed to understand variations in gene expression. This study explores gene expression when individuals are characte...

PURPOSE: This study evaluates the differences in expression of genes frequently analyzed field exercise science between skeletal muscle tissue and various cell types that comprise tissue.METHODS: We summarized proteins expressed were published “Exercise Science” journal from 2015 to present. Thereafter, we selected 15 most muscle. These horizontally compared for components cultured cells based ...

The aim of this study was to assess the differences in correlation of PPARGC1A polymorphisms with type 2 diabetes (T2D) risk in adults of African origins: African Americans and Haitian Americans. The case-control study consisted of >30 years old, self-identified Haitian Americans (n = 110 cases and n = 116 controls) and African Americans (n = 124 cases and n = 122 controls) living in South Flor...

BACKGROUND Sirt6 has been implicated in the regulation of hepatic lipid metabolism and the development of hepatic steatosis. The aim of this study was to address the potential role of Sirt6 in the protective effects of rosiglitazone (RGZ) on hepatic steatosis. METHODS To investigate the effect of RGZ on hepatic steatosis, rats were treated with RGZ (4 mg·kg⁻¹·day⁻¹) by stomach gavage for 6 we...

Certain "degradation" products of GLP-1 were found to possess beneficial effects on metabolic homeostasis. Here, we investigated the function of the COOH-terminal fragment of GLP-1, the nonapeptide GLP-1(28-36)amide, in hepatic glucose metabolism. C57BL/6 mice fed a high-fat diet (HFD) for 13 wk were injected intraperitoneally with GLP-1(28-36)amide for 6 wk. A significant reduction in body wei...

This study was conducted to determine the mechanisms implicated in the beneficial effects of apple polyphenols (APs) against diet-induced obesity in Wistar rats, described in a previous study from our group. Supplementation of high-fat sucrose diet with AP prevented adiposity increase by inhibition of adipocyte hypertrophy. Rats supplemented with AP exhibited improved glucose tolerance while ad...