نتایج جستجو برای: potassium polymorphism

تعداد نتایج: 184444  

2005
Heidi Fodstad

..... ..................................................................................................................................................................... 9 INTRODUCTION .................................................................................................................................................................. 11 REVIEW OF THE LITERATURE ......................

Journal: :The Journal of clinical investigation 2005
Benoit Drolet Chantale Simard Laura Mizoue Dan M Roden

Expression of voltage-gated K channel, shaker-related subfamily, member 5 (KCNA5) underlies the human atrial ultra-rapid delayed rectifier K current (I(Kur)). The KCNA5 polymorphism resulting in P532L in the C terminus generates I(Kur) that is indistinguishable from wild type at baseline but strikingly resistant to drug block. In the present study, truncating the C terminus of KCNA5 generated a...

Journal: :The American journal of clinical nutrition 2010
Bei Sun Jonathan S Williams Laura P Svetkey Nikheel S Kolatkar Paul R Conlin

BACKGROUND Beta(2)-adrenergic receptor (beta2-AR) is a susceptibility locus for hypertension, and polymorphisms at this site relate to salt sensitivity and low plasma renin activity (PRA). The Dietary Approaches to Stop Hypertension (DASH) dietary pattern lowers blood pressure and appears to interact with the renin-angiotensin-aldosterone system (RAAS). OBJECTIVE We hypothesized that the DASH...

Journal: :Discrete Mathematics & Theoretical Computer Science 2022

We assign a relational structure to any finite algebra in canonical way, using solution sets of equations, and we prove that this is polymorphism-homogeneous if only the itself polymorphism-homogeneous. show polymorphism-homogeneity also equivalent property algebraic (i.e., systems equations) are exactly those tuples closed under centralizer clone algebra. Furthermore, aforementioned properties...

Alireza Jafarnejadi, Seyed Mohammadhadi Mousavifazl

Increasing the area of arable oilseed land, particularly rapeseed, and the important role of potassium in yield and oil content, especially in calcareous and high pH soils, need to more knowledge about plant nutrition requirement. In this study, the effect of sources and different levels of potassium fertilizers on some quality and quantity characteristics on canola yield were assessed by combi...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2004
Michel E Safar Malika Lajemi Annie Rudnichi Roland Asmar Anathase Benetos

UNLABELLED Background- Few studies have examined the possible influence of gene polymorphisms on the increase of systolic blood pressure (SBP) and pulse pressure (PP) with age, although in older populations, SBP>160 mm Hg or PP>60 mm Hg are strong mechanical factors predicting cardiovascular mortality. METHODS AND RESULTS This cross-sectional study involved 315 men and 154 women with either s...

2016
Mikayel Aznauryan Siri Søndergaard Sofie L. Noer Birgit Schiøtt Victoria Birkedal

G-quadruplexes (G4s) are DNA secondary structures that are capable of forming and function in vivo The propensity of G4s to exhibit extreme polymorphism and complex dynamics is likely to influence their cellular function, yet a clear microscopic picture of their folding process is lacking. Here we employed single-molecule FRET microscopy to obtain a direct view of the folding and underlying con...

2015
Nai-Jia Liu Hui-Hui Wu Yan-Liang Li Zhen Yang Xiao-Ming Tao Yan-Ping Du Xuan-Chun Wang Bin Lu Zhao-Yun Zhang Ren-Ming Hu Jie Wen

BACKGROUND Genome-wide association studies (GWAS) have reported that the polymorphism rs5219 of the potassium inwardly rectifying channel, subfamily J, member 11 (KCNJ11) is associated with type 2 diabetes mellitus (T2DM). Given that diabetic retinopathy (DR) is one of the most common microvascular complications of T2DM, GWAS have identified a number of potential susceptibility genes for DR. Ho...

Journal: :Hypertension 2011
Cara J Büsst Lisa D S Bloomer Katrina J Scurrah Justine A Ellis Timothy A Barnes Fadi J Charchar Peter Braund Paul N Hopkins Nilesh J Samani Steven C Hunt Maciej Tomaszewski Stephen B Harrap

Variants in the gene encoding the γ-subunit of the epithelial sodium channel (SCNN1G) are associated with both Mendelian and quantitative effects on blood pressure. Here, in 4 cohorts of 1611 white European families composed of a total of 8199 individuals, we undertook staged testing of candidate single-nucleotide polymorphisms for SCNN1G (supplemented with imputation based on data from the 100...

Journal: :American journal of hypertension 2004
Annie Rudnichi Michel E Safar Malika Lajemi Athanase Benetos

BACKGROUND Few studies have examined to what extent genes might modulate the changes of systolic and diastolic blood pressure (BP) with age although, in older populations, systolic BP and diastolic BP vary with age in opposite directions. METHODS This study involved 205 men and 99 women with either systolic-diastolic or isolated systolic hypertension. Age was > 50 years. Using polymerase chai...

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