The resting membrane potential of the lobster axon becomes 5-8 mv more negative when the temperature of the perfusion solution is increased 10 degrees C. This potential change is about twice that predicted if the axon membrane potential followed that expected for a potassium ion electrode potential. When the inhibitors, 2, 4-dinitrophenol, sodium cyanide, and sodium azide, were added separately...

Potassium channels are trans-membrane proteins, which selectively transport K+ ions across cell membranes and play a key role in regulating the physiology of excitability cells and signal transduction pathways. Bothutous Schach (BS) scorpion venom consists of several polypeptides that could modulate ion channels. In this study, the effects of BS crude venom on passive and active electrophysiolo...

Potassium Channels allow potassium flux and are essential for the generation of electric current acrossexcitable membranes. Potassium Channels are also the targets of various intracellular controlmechanisms; such that the suboptimal regulation of channel function might be related to pathologicalconditions. Realistic studies of ion current in biologic channels present a major challenge for compu...

Micro-spherical hard carbon (MSHC) anodes from eco-friendly and adverse precursors with scalability benefits, cost-effectiveness, environmental sustainability in non-aqueous sodium-ion potassium-ion batteries.

The voltage-gated KCNQ1 potassium ion channel interacts with the type I transmembrane protein minK (KCNE1) to generate the slow delayed rectifier (IKs) current in the heart. Mutations in these transmembrane proteins have been linked with several heart-related issues, including long QT syndromes (LQTS), congenital atrial fibrillation, and short QT syndrome. Off-target interactions of several dru...

This work studied simultaneous removal of ammonium and potassium ions by ion exchange with the natural zeolite clinoptilolite. Synthetic and real RO permeate used in experiments contained approximately 250 mg NH4/L and 200 mg K/L. The real RO permeate was obtained from membrane treatment of anaerobically digested cattle manure effluents. Batch experiments were conducted to determine ammonium an...

This communication undertakes to clarify a complex association between potassium distribution and amino acid transport. The transfer of amino acids into cells occurs best over a rather narrow range of extracellular potassium ion concentration (l-4). Furthermore, the uptake of neutral amino acids provokes a somewhat less than stoichiometric loss of potassium from the cells, with sodium ion repla...

The passage of ions across biological membranes is regulated by passive and active mechanisms. Passive ion diffusion into organs depends on the ion-pairing properties of salts present in the serum. Potassium ions could affect brain activity by crossing the blood-brain barrier (BBB) and its accumulation in the extracellular cerebral space could precipitate seizures. In the present study, we anal...

Net sodium influx under K-free conditions was independent of the intracellular sodium ion concentration, [Na](i), and was increased by ouabain. Unidirectional sodium influx was the sum of a component independent of [Na](i) and a component that increased linearly with increasing [Na](i). Net influx of sodium ions in K-free solutions varied with the external sodium ion concentration, [Na](o), and...