There is an increase in population of elderly above the age of 65. As age advances, more diseases develop resulting in use of more medications. Physiological changes, alterations in homeostatic regulation and diseases modify pharmacokinetics and drug response in older patients. The risk for drug interactions and drug-related problems increases along with multiple medications. Periodic evaluatio...

Conversion between anti-epilectic drugs (AEDs) is frequently necessary in epilepsy care, exposing patients to a risk of incurring adverse effects and reduced quality of life. Little practical guidance is available to practitioners to guide conversions between AED monotherapies, or in adding a new adjunctive AED into a polytherapy regimen. This article reviews the impact of adverse effects of AE...

Objectives: The present study evaluated patterns of the use of antiepileptic drugs (AEDs) and their impact on quality of life (QOL) in patients with epilepsy. Methods: In this cross-sectional study, patients with epilepsy (age 418 years) receiving AEDs for at least 1 year were enrolled. Demographic, clinical, and treatment parameters were recorded. QOL was measured using the modified Quality of...

The proper drug choice determines the treatment quality for a disease. pharmacotherapeutic strategy respiratory diseases often involves combination of different drugs with mechanisms action. Salbutamol is short-acting β2-agonist (SABA) used as reliever in asthma and frequently paired inhaled corticosteroids (ICS). Indeed, drug–drug interactions (DDI) receive special attention they are some most...