نتایج جستجو برای: polysaccharide peptide

تعداد نتایج: 180134  

Journal: :Journal of bacteriology 1968
I Azuma H Kimura Y Yamamura

Wax D fraction extracted from human tubercle bacilli is a macromolecular peptide-glycolipid consisting of mycolic acid, polysaccharide, and peptide. Wax D fraction obtained from human tubercle bacilli showed characteristic biological activities such as adjuvant activity in the immune response, the induction of adjuvant arthritis in rats, and growth factor activity for pathogenic Leptospira when...

2015
Hong-Bo Li Miao-Yan Wang Liang-Bin Hu Hai-Zhen Mo

Purpose: To identify the structures of cellulose-extract derivative (CED) formed by heating Lentinus edodes cellulose in water surroundings that can efficiently inhibit aflatoxin production by Aspergillus flavus. Methods: CED was purified on Sepharose CL-6B columns, and then structurally characterized using amino acid analyzer, gas chromatography, Fourier transform infrared spectroscopy, and po...

2015
Julian Ihssen Jürgen Haas Michael Kowarik Luzia Wiesli Michael Wacker Torsten Schwede Linda Thöny-Meyer

Conjugate vaccines belong to the most efficient preventive measures against life-threatening bacterial infections. Functional expression of N-oligosaccharyltransferase (N-OST) PglB of Campylobacter jejuni in Escherichia coli enables a simplified production of glycoconjugate vaccines in prokaryotic cells. Polysaccharide antigens of pathogenic bacteria can be covalently coupled to immunogenic acc...

Journal: :Molecules 2012
Wei-Ting Hung Shwu-Huey Wang Yi-Ting Chen Hui-Ming Yu Chung-Hsuan Chen Wen-Bin Yang

MALDI-TOF MS provides rapid and sensitive analyses of larger biomolecules. However, MS analyses of polysaccharide have been reported to have lower sensitivity compared to peptides and proteins. Here, we investigated some polysaccharides chemically derivatized by permethylation and ortho-phenylene diamine (OPD) tagging. Methylated glycan is obviously able to improve the sensitivity for mass spec...

Journal: :The Journal of pharmacology and experimental therapeutics 2000
K A Witt J D Huber R D Egleton T P Davis

Insulin crosses the blood-brain barrier (BBB) via receptor-mediated transcytosis and has been suggested to augment uptake of peripheral substances across the BBB. The delta-opioid receptor-selective peptide D-penicillamine(2,5) (DPDPE), a Met-enkephalin analog, produces analgesia via a central nervous system-derived effect. In vitro (K(cell), microl. min(-1). mg(-1)) and in situ (K(in), microl....

Journal: :Molecular medicine reports 2012
Zhenwei Shen Han Lei

Human β-defensin-2 (hBD-2) is an antimicrobial peptide with high activity and broad spectrum activity. hBD-2 expression may be highly elevated by microorganisms and inflammation. We reported that the majority of common vaccines used, including 23-valent pneumococcal polysaccharide vaccine, Haemophilus influenzae type b vaccine and split influenza virus vaccine, could induce the expression of hB...

Journal: :Journal of immunology 2002
Zheng-Qi Wu Yi Shen Abdul Q Khan Ching-Liang Chu Richard Riese Harold A Chapman Osami Kanagawa Clifford M Snapper

Little is known concerning the role of T cells in regulating an anti-polysaccharide Ig response to an intact pathogen. We previously reported that the in vivo Ig responses to Streptococcus pneumoniae (strain R36A), specific for pneumococcal surface protein A (PspA) and for the phosphorylcholine (PC) determinant of C-polysaccharide, were both dependent on TCR-alphabeta(+) T cells and B7-dependen...

Journal: :applied biotechnology reports 0
ali mohammad latifi applied biotechnology research center, baqiyatallah university of medical sciences, tehran, iran ehsan sadegh nejad hamid babavalian

the alginate was extracted with six different methods from iran south seacoast algae, sargassum sp, and the percentage yield of alginate was determined. we divided our methods to two groups including acidic extraction and non-acidic. in acidic methods, hcl and h 2 so 4 were used as a detergent in extraction process and cacl 2 was exerted in non-acidic treatments. all treatments compared with ea...

2017
Longbao Zhu Fei Ge Liangjun Yang Wanzhen Li Shenghua Wei Yuigui Tao Guocheng Du

BACKGROUND Alginate is a natural polysaccharide obtained from brown algae and has been shown to have numerous applications in biomedical science, such as wound healing, delivery of bioactive agents, and cell transplantation. Ovalbumin (OVA) peptide 323-339 has been reported to be involved in immune response.  MATERIAL AND METHODS This work investigated the use of alginate particles as a carrier...

Journal: :Journal of agricultural and food chemistry 2004
Christopher M Aberg Tianhong Chen Ayotunde Olumide Srinivasa R Raghavan Gregory F Payne

Tyrosinase was used to initiate the grafting of peptides onto the amine-containing polysaccharide chitosan. Chemical evidence for covalent grafting was obtained from electrospray mass spectrometry for products formed from reactions with glucosamine (the monomeric unit of chitosan) and the model dipeptide Tyr-Ala. When this model dipeptide was incubated with tyrosinase and chitosan, there was a ...

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