The indirect approach to continuous-time system identification consists in estimating continuous-time models by first determining an appropriate discrete-time model. For a zero-order hold sampling mechanism, this approach usually leads to a transfer function estimate with relative degree 1, independent of the relative degree of the strictly proper real system. In this paper, a refinement of the...

This study proposes an artificial hummingbird algorithm (AHA) for energy management (EM) optimal operation of a microgrid (MG), including conventional sources and renewable (RES), with incentive-based demand response (DR). Due to the stochastic nature solar wind output power uncertainty prices load, probabilistic EM hybrid AHA point estimation method (PEM) is proposed model this by utilizing no...

Personality disorders (PDs), long thought to be immutable over time, show considerable evidence of individual change and malleability in modern prospective longitudinal studies. The factors responsible for the evident individual change in PDs over time, however, remain essentially unknown. A neurobehavioral model that posits negative emotion (NEM), nonaffective constraint (CON), communal positi...

Using data from extensive vibrational tests of the new aircraft Saab three di erent methods for vibration analysis are studied These methods are ERA eigensystem realization algorithm N SID a subspace method and PEM prediction error approach We nd that both the ERA and N SID methods give good initial model parameter estimates that can be further improved by the use of PEM We also nd that all met...

Pemetrexed (PEM) is currently recommended as one of the standard anticancer drugs for malignant pleural mesothelioma (MPM). However, the mechanism of the sensitivity of MPM to PEM remains unclear. We analyzed the antitumor effects of PEM in six MPM cell lines by MTS assay. To identify genes associated with drug sensitivity, we conducted gene expression profiling on the same set of cell lines us...

The process personnel always seek the opportunity to improve the processes. One of the essential steps for process improvement is to quickly recognize the starting time or the change point of a process disturbance. Different from the traditional normally distributed assumption for a process, this study considers a process which follows a gamma process. In addition, we consider the possibility o...

Methods for the direct detection of copy number variation (CNV) genome-wide have become effective instruments for identifying genetic risk factors for disease. The application of next-generation sequencing platforms to genetic studies promises to improve sensitivity to detect CNVs as well as inversions, indels, and SNPs. New computational approaches are needed to systematically detect these var...

Explorations of the qualitative and quantitative differences between the odors of pemenone (PEM), androstenone (AND) and isovaleric acid (IVA) show that they share a number of common perceptual characteristics. Among these are similarities in their odor quality and relative intensity ratings. PEM is also an efficient cross-adaptor and modulator of a subject's AND sensitivity. Here we evaluate t...

Pemetrexed (PEM), a multi-targeted antifolate, has promising clinical activity in non-squamous non-small cell lung cancer. However, the majority of patients eventually acquire resistance to PEM. To evaluate the resistant mechanisms, the A549 lung adenocarcinoma cell line was exposed to stepwise increasing PEM concentrations of 1.6, 6.4 and 16 μM to establish three PEM-resistant lung cancer cell...