The production of MG (methylglyoxal) in bacterial cells must be maintained in balance with the capacity for detoxification and protection against this electrophile. Excessive production of MG leads to cell death. Survival of exposure to MG is best understood in the Gram-negative bacteria. The major mechanism of protection is the spontaneous reaction of MG with GSH to form hemithiolacetal, follo...

Large magnetocrystalline anisotropy energy (MAE) is a critical requirement for nanomagnets for applications in magnetic memory and storage devices. Due to small spin-orbit interaction the MAE of ferromagnetic films or single molecule magnets based on 3d metals is small and in typical magnetic nanostructures it is of the order of 2-3 meV. We show that MAE as high as 140 meV can be achieved by ap...

Between 1822 and the late 1830s a highly personal priority dispute was fought between the celebrated surgeon and anatomist Sir Charles Bell and his ex-student Herbert Mayo. The dispute was over the motor and sensory functions of the Vth and VIIth cranial nerves. Over the course of the 1820s and the 1830s, the competing claims of Bell and Mayo were presented in newspapers, journals, and textbook...

The presence of a bulky peripheral wedge destabilizes the homo-assembly of an amide functionalized acceptor (A) monomer and thereby enables the formation of an alternating supramolecular copolymer with an amide appended donor (D) monomer via the synergistic effect of H-bonding and the charge-transfer (CT) interaction with a remarkably high Ka of 31 000 M-1. In sharp contrast, H-bonding driven h...

altan derivatives of polycyclic conjugated hydrocarbons were recently introduced and studied in theoretical organic chemistry. we now provide a generalization of the altan concept, applicable to any graph. several earlier noticed topological properties of altan derivatives of polycyclic conjugated hydrocarbons are shown to be the properties of all altan derivatives of all graphs. among these ar...

let g be a (p,q) graph. an injective map f : e(g) → {±1,±2,...,±q} is said to be an edge pair sum labeling if the induced vertex function f*: v (g) → z - {0} defined by f*(v) = σp∈ev f (e) is one-one where ev denotes the set of edges in g that are incident with a vertex v and f*(v (g)) is either of the form {±k1,±k2,...,±kp/2} or {±k1,±k2,...,±k(p-1)/2} u {±k(p+1)/2} according a...

http://www.bmj.com/content/341/bmj.c6979.full?sid=0c9ee36b-72ab-409a-b94b4e7ba1a7c408 Cite this as: BMJ 2010; 341:c6979 Integrative medicine and the point of credulity 1. John C McLachlan, professor of medical education + Author Affiliations 1. School of Medicine and Health, Durham University, Stockton-on-Tees TS17 6BH, UK 1. [email protected] So called integrative medicine should not ...

a emph{signed graph} (or, in short, emph{sigraph}) $s=(s^u,sigma)$ consists of an underlying graph $s^u :=g=(v,e)$ and a function $sigma:e(s^u)longrightarrow {+,-}$, called the signature of $s$. a emph{marking} of $s$ is a function $mu:v(s)longrightarrow {+,-}$. the emph{canonical marking} of a signed graph $s$, denoted $mu_sigma$, is given as $$mu_sigma(v) := prod_{vwin e(s)}sigma(vw).$$the li...