Pleomorphic adenoma is the most common form of major salivary gland tumors,but it is exceedingly rare in the trachea. We present a case of pleomorphic adenoma of the trachea in an 80-years-old man. Chest three-dimensional CT demonstrated a bosselated mass with a lobulated surface arising from the membranous portion of the upper trachea. Transbronchoscopic biopsy from the mass showed a biphasic ...

Background: Mucoepidermoid carcinoma ex-pleomorphic adenoma (MECxPA) is an extremely rare salivary gland malignancy. With only nine prior reported cases, this entity represents a challenging histopathological diagnosis. Methods: We present a case of a 71-year-old male with an enlarging left neck mass over several months. CT showed both a parapharyngeal space mass and a separate level II neck ma...

BACKGROUND Carcinoma ex pleomorphic adenoma is a rare histologic subtype of salivary gland cancer with an overall poor prognosis. Limited histopathologic analyses have shown that some such tumors exhibit significant HER2/neu immunoreactivity, suggesting a potential role for HER2-based therapy. We report here a case of a 58-year old man with metastatic carcinoma ex pleomorphic adenoma who achiev...

Background: Pleomorphic adenoma (PA) is a benign salivary gland tumour with high incidence and recurrence after treatment. It may recur the same appearance or develop toward malignancy, namely as carcinoma ex pleomorphic (CXPA). Howthis can transform into CXPA remains unclear. Purpose: The aim of this study was to analyse possibility pathogenesis progressivity PA CXPA. Methods: Twenty-four samp...

Introduction Pleomorphic adenoma, also known as mixed tumor, is the most common benign tumor of the major and minor salivary glands. The occurrence of pleomorphic adenoma of the tongue base is very rare, and very few cases have been reported in the literature. Objective The authors present a rare case of pleomorphic adenoma of the tongue base and a review of the literature. Case Report A 55-yea...

A case of salivary gland type pleomorphic adenoma of the trachea in a 48-year-old woman is presented. Pleomorphic adenoma is extremely rare in the trachea. The behavior of this tumor in the trachea appears to be similar to its counterpart in other sites and distinctly different from the more frequently encountered epithelial tumors.

The most common benign salivary gland tumor is pleomorphic adenoma. They can attain giant proportions and weigh several kilograms. They can cause facial disfigurement and, if untreated, could lead malignant transformation. This image depicts a 7.5 kg pleomorphic adenoma of right submandibular gland with malignant change in a 55-year-old male.

Pleomorphic adenoma is the most common neoplasm of the parotid gland. It is associated with the risk of recurrence and malignant transformation. Tumor spillage, incomplete excision, and violation of the tumor pseudocapsule are considered the only proven factors contributing to recurrent disease. The upward spread of recurrent pleomorphic adenoma along the fallopian canal via the stylomastoid fo...