Antibody-free approaches for quantitative LC-MS/MS-based protein bioanalysis are reviewed and critically evaluated, and compared with the more widely used immunoaffinity-based approaches. Antibody-free workflows will be divided into four groups and discussed in the following order: direct analysis of signature peptides after proteolytic digestion; enrichment of target proteins and signature pep...

The amorphous platinum greens, which were synthesized from Pt ( N H s ) ~ ( H ~ O ) ~ (N03)2 or from Pt(NH3)2(H20)2(S04) and uridine, 5-bromouridine and ftorafur, were studied in the solid state by anomalous small angle x-ray scattering. The intensity curves exhibit a power-law dependence, which is likely to originate from large aggregates that are quite compact yet have rough surfaces. The sur...

Platinosis (severe dermatitis and/or asthma) may be broadly defined as the effects of soluble platinum salts on people exposed to them occupationally. Platinum coordination complexes are widely used in the treatment of a variety of solid tumors. However, the clinical use of cisplatin (the most useful agent) is limited by the development of nephrotoxicity. High dose exposure of soluble platinum ...

The research on synthesis of carbon from rice groats at various pyrolysis temperatures and its application for the recovery chromium wastewater tannery industry by varying 300, 400, 500 °C. results are analyzed in form determination yield, water content, ash iodine number. best condition with quality requirement is a temperature °C 760 mg.g-1 (iodine number). Adsorption kinetics was also carrie...

We demonstrate here the first focused electron-beam-induced deposition (EBID) of nanostructures using a liquid precursor. We have deposited sub-50 nm platinum (Pt) wires and dots from a dilute, aqueous solution of chloroplatinic acid. Existing EBID processes rely on the electron-beam stimulated decomposition of gaseous precursors; as a result, the deposits are highly contaminated (up to 75 at. ...

The cyclic voltammetry of both bulk manganese sulfate (BMS) and nano manganese sulfate (NMS) were studied using 0.1M KCl supporting electrolyte and glassy carbon working electrode. The redox behavior for both bulk (BMS) and MnSO4 (NMS) sulfate was studied voltammetrically in presence and absence of Doxorubicin (DR) using three electrodes system, silver- silver chloride (Ag/AgCl), pla...

The kinetics of the reaction between Iäaq and S^O^g has been studied under conditions of production of iodine at a known rate by the persulfate-iodide reaction and its consumption by 5..03 . The effective concentration of iodine during the steady state is measured from its reduction potential at a bright platinum foil electrode. The reaction is of first order with respect to I3~ and 5..03 indiv...

Indoles are omnipresent in natural products, bioactive molecules, and organic materials. Consequently, their synthesis or functionalization are important fields of research in organic chemistry. Most works focus on installation or modification of the pyrrole ring. To access benzene-ring-functionalized indoles with an unsubstituted pyrrole ring remains more challenging. Reported herein is a plat...

The cyclic voltammetry of both bulk manganese sulfate (BMS) and nano manganese sulfate (NMS) were studied using 0.1M KCl supporting electrolyte and glassy carbon working electrode. The redox behavior for both bulk (BMS) and MnSO4 (NMS) sulfate was studied voltammetrically in presence and absence of Doxorubicin (DR) using three electrodes system, silver- silver chloride (Ag/AgCl), pla...