Background: Recent improvement in treatments of cancer has significantly increased survival rates of cancer patients. Unfortunately these treatments such as chemotherapy and radiotherapy can sever damage to the ovaries. Ovarian cryopreservation prior to chemo/ radiotherapy and auto-transplantation post-treatment can restore fertility to cancer patients. Hypoxia in the transplant from delayed re...

OBJECTIVES Mesenchymal stem cells have the ability to differentiate into various cell types, and thus have emerged as promising alternatives to chondrocytes in cell-based cartilage repair methods. The aim of this experimental study was to investigate the effect of bone marrow derived mesenchymal stem cells combined with platelet rich fibrin on osteochondral defect repair and articular cartilage...

The composition of an evolving arterial thrombus may be a determinant of how effectively pharmacologic agents prevent reocclusion after initially successful thrombolysis. In this study, reoccluding plateletor fibrin-rich thrombi as delineated by scanning electron microscopy were produced selectively in the femoral arteries of dogs with the use of electrically induced vascular injury or implanta...

AMA Utomo Y, Sulistyani LD. Platelet-rich fibrin in combination with mandibular or maxillary non-vascularized bone graft: a systematic review. Journal of Stomatology. 2023;76(2):128-135. doi:10.5114/jos.2023.128819. APA Utomo, Y., & Sulistyani, L. D. (2023). Stomatology, 76(2), 128-135. https://doi.org/10.5114/jos.2023.128819 Chicago Yudy Ardilla, and Lilies D Sulistyani. 2023. "Platelet-rich r...

BACKGROUND Periodontitis is characterized by the formation of true pockets, bone loss and attachment loss. Various techniques have been attempted in the past to truly regenerate the lost periodontal structures, albeit with variable outcome. In this evolution, the technique being tried out widely is the use of platelet rich concentrates, namely platelet-rich fibrin (PRF). CASE DESCRIPTION In t...

HIGHLIGHTS Alginate/Chitosan is the second most abundant polysaccharide on earth. PRF (platelet-rich fibrin) potential to play adjunct roles in regenerative medicine. 3D printing grafts can increase wound healing capacity. Prospective of combining with different biomaterials promotes tissue regeneration.

Platelet concentrates for surgical use are autogenous regenerative preparations, produced by the centrifugation of the patient own blood sample. Most techniques are often regrouped inappropriately under the historical term of Platelet-Rich Plasma (PRP). Since 15 years, their use dramatically increased in many surgical fields, particularly in oral and maxillofacial surgery. The literature on thi...