cancer is still one of the major causes of mortality in both developing and developed countries. at this time, in spite of intensive interventions, a large number of patients have poor prognosis. therefore, the effort for finding new anticancer agents with better efficacy and lesser side effects has continued. according to the traditional recommendations and experimental studies, numerous medic...

approximately 25% of all oral cavity carcinomas involve the lips, and the primary management of these lesions is complete surgical resection. loss of tissue in the lips after resection is treated with a variety of techniques, depending on the extension and location of the defect. here we review highly accepted techniques of lip reconstruction and some of new trials with significant clinical res...

background and objective: wilms’ tumor has been recognized as the most common primary malignancy of kidney at childhood, comprises 5-6% of tumors in this period, and manifests itself with various clinical symptoms. since there have been no sufficient studies in this field in iran, therefore, this study was conducted to investigate its histopathology and clinical symptoms. materials and methods:...

introduction: bombesin (bn), a 14-amino acid neuropeptide, shows high affinity for the human grp (gastrin releasing peptide) receptors, which are overexpressed by a variety of cancers, including prostate, breast, pancreas, gastrointestinal, and small cell lung cancer. aim was to prepare [6-hydrazinopyridine-3-carboxylic acid (hynic0), d-tyr6, d-trp8] - bn [6-14] nh2 that could be easily labeled...

introduction paragangliomas are mostly localized in the adrenal medulla and they are usually pheochromocytomas, derived from the neural crest, but otherwise mesenteric paragangliomas are extremely rare tumors. case presentation in this article we represent a 59-year-old female with an abdominal mass and pain due to mesenteric paraganglioma. conclusions paragangliomas can occur as mesenteric tum...

osteosarcoma (os) is a malignant mesenchymal tumor, which rarely occurs in the maxilla. although variable histologic and radiographic features of os have been reported previously, in the majority of the cases painful swelling of the jaw is mentioned as the first clinical presentation. furthermore, early diagnosis and wide surgical resection of the tumor are the most important determinant factor...

purpose: to assess the relative frequencies of etiologies leading to eye removal in patients who referred to feiz hospital, isfahan, between 2011 and 2014. methods: this retrospective study was conducted on patients who underwent eye removal at feiz hospital. age, sex, eye laterality, underlying etiology, visual acuity, and surgical technique (enucleation, evisceration, or exenteration) were re...

chondrosarcoma is the second most common primary mesenchymal malignant tumor of the bone. the most common form is central chondrosarcoma and the rarest is intracortical chondrosarcoma. here, we describe the clinical, pathological, and imaging features of a case of intracortical chondrosarcoma as well as the outcome of surgical treatment. this is the third case reported in the literature.

background: rahbdoid tumor of kidney (rtk) is a childhood rare neoplasm, previously thought as a sarcoma variant of wilms’ tumor, but now is recognized as a distinct pathologic entity. method : we report a pathologically proved case of rtk, associated with brain mass in a 4.5-month-old girl that has referred for gross hematuria. shortly after initiating chemotherapy, because of retractile vomit...

how to cite this article: tabatabaei sm, seddighi a, seddighi as. posterior fossa tumor in children. iran. j. child. neurol 2012;6(2): 19-24.   objective primary brain tumors are the most common solid neoplasms of childhood, representing 20% of all pediatric tumors. the best current estimates place the incidence between 2.76 and 4.28/100,000 children per year. compared with brain tumors in adul...