Submitted by drupal on Thu, 10/23/2014 13:43 Firm: IAVO Research and Scientific [2] Award Solicitation: NASA SBIR 2012 Phase II Solicitation [3] Award ID: SBIR_12_P2_125267 Award Topic: Fault Management Technologies [4] Award Dollars: 749 667.00 Award Lead Center: Marshall Space Flight Center [5] Proposal Number: S5.05-8733 Proposal Title: A Real-Time Fault Management Software System for Distri...

Submitted by drupal on Thu, 10/23/2014 13:51 Firm: Crystal Research, Inc. [2] Award Solicitation: NASA SBIR 2014 Phase I Solicitation [3] Award ID: SBIR_14_P1_144558 Award Topic: In Situ Sensors and Sensor Systems for Lunar and Planetary Science [4] Award Dollars: 123 861.00 Award Lead Center: Ames Research Center [5] Proposal Number: S1.06-9443 Proposal Title: A Pulsed Nonlinear Raman Detectio...

The polypeptide patterns of MCF-7 human breast cancer cells (MCF7gpt) and a stably v-H-roi-transfected subclone (MCF-7ras) have been analyzed following estradili! treatment. Since both estradili! and \-H-ras transfection increase tumorigenicity of MCF-7 cells, this study was designed to ascertain if specific changes in polypeptides were common in both treatments. Separation of cellular and secr...

Bone marrow samples from 33 patients affected by MM and MGUS, and 8 patients not affected by lymphoproliferative diseases were studied for expression of c-Jun (a component of the transcription factor AP-1) and glutathione-S-transferase pi (GST-pi) using immunocytochemical methods. A high and frequent expression of these two proteins was found both in MM and MGUS patients (31/33 patients positiv...

Activation of the phosphatidylinositol-3 kinase (PI 3-K) pathway is associated with the proliferation of many cell types, including T lymphocytes. However, recent studies in cell lines stably expressing deletion mutants of IL-2R that fail to activate PI 3-K have questioned the requirement for this pathway in cell cycle regulation. In this study with IL-2 and IL-7, we show in primary T cells tha...

The present study was carried out to assess the effects of protease inhibitor (PI) therapy on basal whole body protein metabolism and its response to acute amino acid-glucose infusion in 14 human immunodeficiency virus (HIV)-infected patients. Patients treated with PIs (PI+, 7 patients) or without PIs (PI-, 7 patients) were studied after an overnight fast during a 180-min basal period followed ...

Using a hormonally induced susceptibility mouse model to investigate vaginal HSV type 2 (HSV-2) infection, a study was undertaken to determine the efficacy of a plasmid DNA encoding IFN-alpha1 introduced into the vaginal lumen postinfection (PI). Mice infected with HSV-2 intravaginally and treated intravaginally 24 h later with 100 microg DNA encoding IFN-alpha1 showed enhanced survival (10/15)...

OBJECTIVE To estimate prevalence of cattle persistently infected (PI) with bovine viral diarrhea virus (BVDV) at arrival at a feedlot, prevalence of chronically ill and dead PI cattle, and the magnitude of excess disease attributable to a PI animal. DESIGN Cross-sectional and cohort studies. ANIMALS 2,000 cattle at the time they arrived at a feedlot, 1,383 chronically ill cattle from 7 feed...

Diacylphosphatidylinositol (PI) is the starting reactant in the process of phosphatidylinositide-related signal transduction mediated through the lipid raft domain. We investigated intermolecular interactions of PI with major raft components, sphingomyelin (SM) and cholesterol (Chol), using surface pressure-molecular area (π-A) isotherm measurements. The classical mean molecular area versus com...