Chemoprevention with food phytochemicals is currently regarded as one of the most attractive strategies for cancer control. We have been continuously working on the identification and characterization of chemopreventive phytochemicals extracted from a diverse range of edible plants. Recently, we have utilized a convenient assay, the tumor promoter-induced superoxide generation test, with differ...

Food ingestions generally regulate many physiological functions to maintain a healthy life. Furthermore, herbal medicine is prescribed for the prevention and the treatment of various diseases. There are not a few herbal medicine-derived drugs (phytochemicals) clinically using now. The phytochemicals such as digitalis, curare, morphine, quinidine, atropine, and so on are so much important drugs ...

Objective: To establish the fingerprint profile of Wedelia chinensis using thin layer chromatography (TLC) and high performance thin layer chromatography (HPTLC) technique. Methods: TLC and HPTLC studies were carried out in two different solvent systems, which showed different Rf value. Results: TLC profiling of the extract confirm about the presence of various phytochemicals. HPTLC finger prin...

objective: the aim of this study was to estimate the cheminformatics and qualitative structure-activity relationship (qsar) of cinnamaldehyde and eugenol. the effects of cinnamaldehyde and eugenol on the viability, doubling time and adipogenic or osteogenic differentiations of human adipose-derived mesenchymal stem cells (hascs) were also investigated.  materials and methods: qsar and toxicity ...

The population is aging. Over the coming years, the incidence of age-related chronic diseases such as cancer is expected to continue to increase. Phytochemicals, which are non-nutritive chemicals found in plants and food, have emerged as modulators of key cellular signaling pathways exerting proven anticancer effects. The challenge now is to develop personalized supplements comprised of specifi...

The present study was carried out to evaluate phytochemicals of pods of Leucaena leucocephala. The phytochemical analysis was performed using 50% ethanolic extracts of pods powder of Leucaena leucocephala. Quantitative analysis of phytochemicals like phenols, flavonoids and tannins was done. Phytochemical analysis revealed the presence of alkaloids, flavonoids, phenols, tannins, saponins, carbo...

Pain in cancer therapy is a common condition and there is a need for new options in therapeutic management. While phytochemicals have been proposed as one pain management solution, knowledge of their utility is limited. The objective of this study was to perform a systematic review of the biomedical literature for the use of phytochemicals for management of cancer therapy pain in human subjects...

Aberrant production of immature white blood cells leads to the onset of leukemia. The process of leukemogenesis involves alterations in expressions of various genes and their associated signalling pathways. Existing treatment protocols for leukemia therapy may be quite effective but they pose serious adverse effects on the individual. Therefore, newer means need to be explored which may help to...

White spot syndrome (WSS) is one of the most common and most disastrous diseases of shrimp worldwide. It causes up to 100% mortality within 3 to 4 days in commercial shrimp farms, resulting in large economic losses to the shrimp farming industry. VP28 envelope protein of WSSV is reported to play a key role in the systemic infection in shrimps. Considering the most sombre issue of viral disease ...

There is compelling evidence showing that dietary phytochemicals have exhibited pronounced bioactivities in a number of experimental models. In addition, a variety of epidemiological surveys have demonstrated that frequent ingestion of vegetables and fruits, which contain abundant phytochemicals, lowers the risk of onset of some diseases. However, the action mechanisms by which dietary phytoche...