We present a handheld biosensor system for the label-free and specific multiplexed detection of several biomarkers employing a spectrometer-free imaging measurement system. A photonic crystal surface functionalized with multiple specific ligands forms the optical transducer. The photonic crystal slab is fabricated on a glass substrate by replicating a periodic grating master stamp with a period...

In this paper, a new design of demultiplexer based on two-dimensional photonic crystal ringresonator is proposed. The structure is made of a hexagonal lattice of silicon rods with therefractive index 3.46 in coefficient of air with refractive index 1. The transmission efficiencyand Quality factor for our proposed demultiplexer, respectively, are more than 65% and1600. The normalized transmissio...

We review the development and application of nanostructured photonic crystal surfaces and a hyperspectral reflectance imaging detection instrument which, when used together, represent a new form of optical microscopy that enables label-free, quantitative, and kinetic monitoring of biomaterial interaction with substrate surfaces. Photonic Crystal Enhanced Microscopy (PCEM) has been used to detec...

A label-free biosensor device based on registration of photonic crystal surface waves is described. Angular interrogation of the optical surface wave resonance is used to detect changes in the thickness of an adsorbed layer, while an additional simultaneous detection of the critical angle of total internal reflection provides independent data of the liquid refractive index. The abilities of the...

A surface plasmon resonance (SPR) based photonic crystal fiber (PCF) sensor having a milled microchannel, and an open D-channel has been proposed in this paper. The shows good functionality the wide sensing range of 1.14-1.36 Refractive Index Units (RIU) analyte, capability to detect low refractive index (RI). Finite Element Method (FEM) numerical investigations dictate that able gain maximum w...

In this paper, a Photonic Crystal Fiber (PCF) based Surface Plasmon Resonance (SPR) biosensor for the detection of four bacteria such as Vibrio Cholera, Escherichia Coli (E. coli), Bacillus Anthracis, and Enterococcus Faecalis is proposed evaluated numerically using finite element method (FEM)-based simulation tool. The sensor exhibits excellent performance characteristics has configurat...