A simple, rapid and precise method was developed for the quantitative estimation of prasugrel hydrochloride in pharmaceutical dosage form. A chromatographic separation of prasugrel and its degradants was achieved with Zorbax XDB C(8), 150 × 4.6 mm, 3.5μm analytical column using aqueous solution of 0.05 M ammonium acetate pH 4.5 with acetic acid-acetonitrile (40:60 v/v). The instrumental setting...

Light falling on a photodetector produces an output current that fluctuates. The noise in this signal arises from two sources: randomness in the photon arrivals and randomness in the carrier multiplication process intrinsic to the photodetector. A general formula is derived for the variance of the photodetector output current in terms of parameters characterizing these two sources of randomness...

Preface All products are continuously being improved for better performance. Spectrometers have developed in many ways since the introduction of simple and moderately priced spectrophotometers which were commercially available from the mid 1950’s. 1 Such improvements have enabled SCINCO to manufacture PDA type UV-Vis. spectrophotometers. The scope and performance of conventional single channel ...

A corrected measurement method was investigated for the silicon photodiode detector. The measured transmittance error between detector and light power meter occurs depends on incident power. In our work, non-linear empirical formula derived from results of meter. addition, used to correct measuring polymer-dispersed liquid crystal, are identical those experimental further show that is faster th...

Nowadays, there are two types of sensors to detect the low luminous flux, PMT (Photomultiplier Tube) and Geiger-APD (Geiger Avalanche Photodiode). The domain of Geiger-APD has reached an advanced development in the last years. The basic idea of this structure consists in polarizing an APD in Geiger-mode by applying a voltage beyond its breakdown voltage. In this case of polarization, the APD is...

A compact and flexible circuit for operating avalanche photodiodes in Geiger mode was designed, fabricated, and tested. A new voltage driver stage, based on fast n-channel double-diffused metal– oxide–semiconductor ~DMOS! transistors in a bootstrap configuration, makes it possible to obtain quenching pulses up to 25 V amplitude and fast active reset of the detector. At 20 V excess bias voltage ...

A flow cytometer using a solid state light source and detector was designed and built. For illumination of the sample stream two types of diode lasers (670 nm and 780 nm) were tested in a set-up designed to differentiate human leukocytes by means of light scattering. The detector is an avalanche photodiode, which was used to detect the weak scattered light in the orthogonal direction. The new f...