PBS: Phosphate Buffered Saline; CSPG: Chondroitin Sulfate Proteoglycans; ChABC: Chondroitinase ABC; SUR1–TRPM4 : Sulfonylurea Receptor 1–Transient Receptor Potential Melastatin 4, PTEN: Phosphate and Tensin Homolog; mTOR: Mammalian Target of Rapamycin; SOCS3: Suppressor of Cytokine Signaling 3; BDNF: Brain -Derived Neurotrophic Factor; LINGO-1: Leucine Rich Repeat and Ig Domain Containing 1; Tr...

OBJECTIVE To compare the effects of buffered hypertonic and buffered normal saline nasal spray on mucociliary clearance and nasal airway patency. STUDY DESIGN AND SETTING Double-blind trial with subjects acting as their own controls. Tertiary care academic medical center. RESULTS Buffered hypertonic saline and buffered normal saline both improved saccharine clearance times ( P < 0.0001 for ...

BACKGROUND AND PURPOSE We tested in a rat meningitis model 1) whether pneumococcal cell wall components are capable of producing changes in regional cerebral blood flow, brain water content, and intracranial pressure similar to those we have already observed after intracisternal inoculation of live pneumococci and 2) whether antioxidants would modulate these alterations in the early phase of me...

background: this study was conducted to assess the effect of thickness and hydration condition on the surface microhardness of endosequence root repair material putty (errm; brasseler usa, savannah, ga), a premixed bioceramic material. materials and methods: polymethyl methacrylate cylindrical molds with an internal diameter of 4 mm and three heights of 2, 4, and 6 mm were fabricated. in group ...

infectious agents cause disease in virtually any susceptible hosts. in the poultry production and medicine, pathogens were eliminated from a line of a breeder by injection of antibiotics into hatching eggs. there is little information available describing the safety of the folate antimetabolite/sulfonamide class of antibiotics on the game birds embryonated eggs. the objective of this study was ...

Folic acid (FA) was immobilized on Eu(3+)-doped nanoporous silica spheres (Eu:NPSs) through mediation of the 3-aminopropyltriethoxysilane adlayer. The ordered nanopores of Eu:NPS were preserved by the immobilization. The FA-immobilized Eu:NPSs showed the characteristic photoluminescence peak due to interactions between the FA molecules and Eu(3+) ions, and highly dispersed stability in phosphat...

Rats were vaccinated with a toxoid (D-toxoid) prepared from purified heat-labile toxin (D-toxin) produced by Pasteurella multocida serogroup D. Vaccination of rats with D-toxoid prevented death and other effects of D-toxin (hepatic necrosis, development of elevated leukocyte counts, lymphopenia, neutrophilia, and elevated complement titers) that occurred in phosphate buffered saline (PBS)-vacci...

Substances cryoprotective for Vibrio cholerae were detected from prawn shells immersed in phosphate-buffered saline. This cryoprotective activity was heat resistant and sensitive to treatment with trypsin. For the exhibition of its full activity, the presence of Mg ion was indispensable. The cryoprotective activity of this substance was more active than that of other known cryoprotectants, like...

Submit Manuscript | http://medcraveonline.com Abbreviations: DM: Diabetes Mellitus; CVDs: Cardiovascular Diseases; PQQ: Pyrroloquinoline Quinone; LDH: Lactate Dehydrogenase; RR-value: Relative Risk Value; LPO: Lipid Peroxidation; LOOH: Lipid Hydroperoxide; HDL-C: High Density Lipoprotein; ROS: Reactive Oxygen Species; MDA: Malondialdehyde; STZ: Streptozotocin; PBS: Phosphate Buffered Saline; BS...