نتایج جستجو برای: phloretin

تعداد نتایج: 478  

2011
Ranokhon S. Kurbannazarova Svetlana V. Bessonova Yasunobu Okada Ravshan Z. Sabirov

Channel-mediated trans-membrane chloride movement is a key process in the active cell volume regulation under osmotic stress in most cells. However, thymocytes were hypothesized to regulate their volume by activating a coupled K-Cl cotransport mechanism. Under the patch-clamp, we found that osmotic swelling activates two types of macroscopic anion conductance with different voltage-dependence a...

2016
Tingjing Zhang Jianqiang Liang Panxue Wang Ying Xu Yutang Wang Xinyuan Wei Mingtao Fan

Phloretin-2'-O-glycosyltransferase (P2'GT) catalyzes the last glycosylation step in the biosynthesis of phloridzin that contributes to the flavor, color and health benefits of apples and processed apple products. In this work, a novel P2'GT of Malus x domestica (MdP2'GT) with a specific activity of 46.82 μkat/Kg protein toward phloretin and uridine diphosphate glucose (UDPG) at an optimal tempe...

2015
Samuel B. Low Edward P. Allen Elias D. Kontogiorgos

OBJECTIVE This clinical study aimed to evaluate effectiveness of a commercially available toothpaste containing potassium nitrate, sodium monoflurophosphate, and nano-hydroxyapatite as well as antioxidants phloretin, ferulic acid and silymarin in reducing dental hypersensitivity in adults. METHODS The clinical trial enrolled patients with a history of dentin hypersensitivity. A test toothpast...

2014
I-Shan Hsieh Rong-Sen Yang Wen-Mei Fu Effie C. Tsilibary

Osteosarcoma is the most common primary malignancy of bone. Even after the traditional standard surgical therapy, metastasis still occurs in a high percentage of patients. Glucose is an important source of metabolic energy for tumor proliferation and survival. Tumors usually overexpress glucose transporters, especially hypoxia-responsive glucose transporter 1 and glucose transporter 3. Osteopon...

Journal: :Stroke 1983
W H Oldendorf P D Crane P M Lawner L D Braun

Rats were injected intravenously with either phloretin (100 mg/kg) or 3-0-methyl glucose (2 g/kg) to reduce the carrier-mediated flux of glucose into brain. Plasma glucose and brain free glucose (BFG), lactate, and glycogen were measured over a 16 min time course. Injection of these substances caused a rapid drop in BFG to 60% of control at one minute and a minimum (50% of control values) at 4 ...

Journal: :Cancer research 1961
L S DIETRICH M J FRIEDLAND

The effects of the synthetic estrogens diethylstilbesterol, hexosterol, dienesterol, and phloretin were compared with their capacity to inhibit the endogenous respiration of intact Ehrlich ascites, Adenocarcinoma 755 ascites, and Ehrlich-Lettr6 ascites cells. The Ehrlich ascites was found to be far more susceptible to respiratory inhibition than either the Adenocarcinoma 755 or the Ehrlich-Lett...

Journal: :General physiology and biophysics 2003
M Kaloyianni I Doukakis

The characteristics of 3-O-methyl-D-glucose (3-OMG) uptake by frog erythrocytes were studied. 3-OMG transport was increased by adrenaline. Although the transport is inhibited by phloretin, the lack of saturation kinetics suggests that a glucose transporter doesn't exist or that its affinity for glucose is extremely low. Frog Rana balcanica red cells suspended in an isotonic medium containing ad...

Journal: :Journal of agricultural and food chemistry 2013
Anupama Ranganathan Grace A Paradise Chad A Hansen Mark R McCoy Shirley J Gee Ping Zhong Dan Chang Bruce D Hammock

Hesperetin dihydrochalcone 4'-glucoside, 1, and phloretin 4'-glucoside, 2, belong to a family of dihydrochalcone glycosides that exhibit flavorant properties. In this study was developed a competitive, indirect homologous ELISA for the detection of targets 1 and 2 in fermentation media. Immunogen and coating antigen were prepared by conjugating hapten, 4-(3-oxo-3-(2,6-dihydroxy-4-glucoside phen...

Journal: :Kidney international 1985
J Rapoport J W Mills N Franki H H Church R M Hays

The autoradiography of diffusible, hydrophilic solutes presents special problems in localization of the labeled solute under study. We present studies of the movement of 14C-labeled urea, and 14C- and 3H-labeled sucrose across the isolated urinary bladder of the toad, a vasopressin-sensitive epithelium, using a technique that avoids exposure to water throughout all processing steps and minimize...

Journal: :The Journal of clinical investigation 1977
W A Kachadorian S D Levine J B Wade V A Di Scala R M Hays

It has been previously demonstrated with freeze-fracture electron microscopy that vasopressin induces specific structural alterations of the luminal membrane of granular cells from toad urinary bladder in a dose-dependent fashion. These alterations consist of aggregated intramembranous particles and are observed both in the presence and absence of an osmotic gradient. We examined the effect of ...

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