Several lines of evidence have indicated that many nuclei in the brain including preoptic nucleus, AV3V, subfornical organ, septal area and lateral hypothalamus are the targets of efferents from chemo-sensitive and pressure-sensitive systems. These areas may concern with regulation of fluid homeostasis. In the present study, intracerebroventricular injections were carried out in all experiments...

MOTIVATION In silico prediction of drug-target interactions from heterogeneous biological data is critical in the search for drugs and therapeutic targets for known diseases such as cancers. There is therefore a strong incentive to develop new methods capable of detecting these potential drug-target interactions efficiently. RESULTS In this article, we investigate the relationship between the...

The no reflow phenomenon is a feared complication in Percutaneous Coronary Intervention (PCI) procedures including elective as well primary PCI (Percutaneous Intervention), and results worse prognosis. A number of etiological factors are involved pathogenesis phenomenon. These include distal athero embolization, ischemic reperfusion injury, microvascular spasm endothelial dysfunction. treatment...