In the present work, we studied the ability of thymol to affect the organization of model membranes and the activity of an intrinsic membrane protein, the GABA(A) receptor (GABA(A)-R). In this last aspect, we tried to elucidate if the action mechanism of this terpene at the molecular level, involves its binding to the receptor protein, changes in the organization of the receptor molecular envir...

the most common type of childhood-onset epilepsy syndrome is childhood absence epilepsy (cae) with well-defined electro clinical features but unknown pathological basis. the incidence of absence epilepsy is about 2 and 8 out of every 100 000 children up to the age of 16, and the prevalence is 2 and 10% of children with any form of epilepsy. children with cae suffer from high rate of pretreatmen...

Hibiscus tiliaceus, locally known as Bhola was examined for phytochemical properties and its cytotoxic, antibacterial, analgesic and neuropharmacological activities using the ethanol extract of leaf and bark. The phytochemical analysis of the leaf extract indicated the presence of tannins, whereas bark extract indicated the presence of alkaloid, reducing sugar and tannins. A preliminary cytotox...

Defining dose requirement, pharmacokinetics and pharmacodynamics Clinical anaesthetists administer doses of drugs to obtain various degrees of drug effect. Some anaesthetic drug effects, such as muscle relaxation, are relatively easy to quantitate, whereas others such as anaesthetic depth are much more difficult. Anaesthetic dose requirement can be defined as the dose of drug that produces a de...

Seaweeds have caused an emerging interest in the biomedical area, mainly due to their contents of bioactive substances which show great potential as anti-inflammatory, anti-microbial, anti-viral and anti-tumoral drugs. Despite the diversity in quality and quantity of the Mediterranean Tunisian coast flora, with its large contains of marine organisms and seaweeds, most of them have not yet been ...

Maslinic Acid a characteristic compound of the triterpenoid bunch got from olive which forestalls age favorable to fiery cytokines and oxidative pressure, found in an assortment common sources, going home grown cures utilized traditional medicine consumable vegetables organic products present Mediterranean eating routine. A few investigations have demonstrated that maslinic acid wide scope phar...

Seaweeds have caused an emerging interest in the biomedical area, mainly due to their contents of bioactive substances which show great potential as anti-inflammatory, anti-microbial, anti-viral and anti-tumoral drugs. Despite the diversity in quality and quantity of the Mediterranean Tunisian coast flora, with its large contains of marine organisms and seaweeds, most of them have not yet been ...