A genetic algorithm (GA) based recurrent fuzzy neural network modeling method for dynamic nonlinear chemical process is presented. The dynamic recurrent fuzzy neural network (RFNN) is constructed in terms of Takagi-Sugeno fuzzy model. The consequent part is comprised of the dynamic neurons with output feedback. The number and the parameters of membership functions in the premise part are optimi...

1. The rate of the saponification of iodoacetic acid in sodium hydroxide and alkaline buffer solutions yielding glycollic acid was measured by means of Heyrovský's polarographic method. 2. From the bimolecular velocity constants, increasing with the ionic strength of the solution, the Brönsted factor, F, which characterizes the primary salt effect, was calculated. 3. In the borate buffer soluti...

BACKGROUND Coagulopathy is an important contributor to morbidity and mortality in trauma patients. Acidosis contributes to coagulopathy. Acidosis can be neutralized with intravascular bicarbonate, but it is unclear if the coagulation defect is rapidly reversed. The effects of acidosis and bicarbonate neutralization on coagulation function were investigated in vivo. METHODS Acidosis was induce...

This article presents a solution to pH control based on model-free intelligent control (MFIC) using reinforcement learning. This control technique is proposed because the algorithm gives a general solution for acid-base system, yet simple enough for its implementation in existing control hardware. In standard reinforcement learning, the interaction between an agent and the environment is based ...

The recombination of hydronium and hydroxide ions following water ionization is one of the most fundamental processes determining the pH of water. The neutralization step once the solvated ions are in close proximity is phenomenologically understood to be fast, but the molecular mechanism has not been directly probed by experiments. We elucidate the mechanism of recombination in liquid water wi...

To be administered to patients, therapeutic monoclonal antibodies must have very high purity, with process related impurities like host-cell proteins (HCPs) and DNA reduced to <100 ppm and <10 ppb, respectively, relative to desired product. Traditionally, Protein-A chromatography as a capture step has been the work horse for clearing a large proportion of these impurities. However, remaining le...

HCO(3)(-) secretion, which is believed to neutralize acid within the mucus gel, is the most studied duodenal defense mechanism. In general, HCO(3)(-) secretion rate and mucosal injury susceptibility correlate closely. Recent studies suggest that luminal acid can lower intracellular pH (pH(i)) of duodenal epithelial cells and that HCO(3)(-) secretion is unchanged during acid stress. Furthermore,...

The process using lignosulfonates for acidic rock drainage (ARD) treatment is referred to as the Lignor TM process. Lignosulfonates are waste by-products produced in the sulfite pulping process. The present study has shown lignosulfonates are able to protect lime from developing an external surface coating, and hence to favor its dissociation. Further, the addition of lignosulfonates to ARD sol...

The poor water solubility and bioactivity of lipophilic phytochemicals can be potentially improved by delivery systems. In this study, a low-cost, low-energy, and organic solvent-free encapsulation technology was studied by utilizing the pH-dependent solubility properties of curcumin and self-assembly properties of sodium caseinate (NaCas). Curcumin was deprotonated and dissolved, while NaCas w...

Carboxymethyl Cellulose (CMC) a compound made from starch of tubers ganyong flour with added methanol, propanol and water. Four process involving alkalization process, karboksimetilasi, neutralization in the making CMC. Carboxymethylization alkazation proess Alkazation is reaction between cellulose soda solution (alkaline) to become alkaline (cellulose soluble solution). rection sodium chloro a...