Kinetic curves for neutralization of adenovirus type 2 with anti-hexon serum revealed no lag periods even when the serum was highly diluted or when the temperature was lowered to 4 degrees C, thus indicating a single-hit mechanism. Multiplicity curves determined with anti-hexon serum displayed a linear correlation between the degree of neutralization and dilution of antiserum. Neutralization va...

In this study, the high-resolution ultrasonic spectroscopy (HR-US) technique was applied to examine interpolyelectrolyte neutralization. The mentioned method tested on example of complexation between poly(allylammonium) cations and poly(acrylate) anions in aqueous solutions at pH = 7. It confirmed by HR-US that type titration (stepwise or abrupt), direction titration, background salt affect out...

The present study investigates the antacid effect of the aqueous extract of the fruit rind of Garcinia indica (GIE) by using a modified artificial stomach model. The pH of GIE (400 mg/kg and 800 mg/kg) and its neutralizing effect on artificial gastric acid was determined and compared with water and the active control sodium bicarbonate. A modified model of Vatier’s artificial stomach was used t...

The binding of vitamin B(12) by human gastric juice has been found to be pH dependent. Maximum binding occurs between pH 6.5 and 10. Outside this pH range the vitamin B(12)-binding ability of human gastric juice decreases and at pH below 2 or above 12.2 this drops sharply to about 10 to 15% of the maximum. Three commercial hog intrinsic factors have been found to give a similar response to pH c...

The effect of three food preservatives, sorbic acid and methyl and butyl esters of p-hydroxybenzoic acid, on the protonmotive force in Escherichia coli membrane vesicles was investigated. Radioactive chemical probes were used to determine the two components of the protonmotive force: delta pH (pH difference) and delta psi (membrane potential). Both types of compound selectively eliminated delta...

Oligodendroglioma is characterized by mutations of IDH and CIC, 1p/19q loss, and slow growth. We found that NHE-1 on 1p is silenced in oligodendrogliomas secondary to IDH-associated hypermethylation and 1p allelic loss. Silencing lowers intracellular pH and attenuates acid load recovery in oligodendroglioma cells. Others have shown that rapid tumor growth cannot occur without NHE-1-mediated neu...

The present paper investigates the rheological properties of silated hydroxypropylmethylcellulose (Si-HPMC) biohydrogel used for biomaterials and tissue engineering applications. The general property of this modified cellulose ether is the occurrence of self-hardening due to silanol condensation subsequent to a decrease in pH (from 12.4 to nearly 7.4). The behavior of unsterilized and sterilize...

In this paper, an adaptive neuro fuzzy sliding mode based genetic algorithm (ANFSGA) controlsystem is proposed for a pH neutralization system. In pH reactors, determination and control of pH isa common problem concerning chemical-based industrial processes due to the non-linearity observedin the titration curve. An ANFSGA control system is designed to overcome the complexity of precisecontrol o...