Periprosthetic fractures of the femur present a challenging surgical problem. The aim of this study was to evaluate the outcome of periprosthetic femoral fractures (PFF) which were treated with internal fixation or stem revision. Depending on the fracture type in the Duncan-Vancouver-Classification, 42 patients with PFF were treated either with a Fixateur interne (n = 23) in cases with type B1 ...

A novel aggregation-based biosensing method to achieve detection of oligonucleotides in a pinched-flow fractionation (PFF) microseparator was developed. Employing functionalized polystyrene microspheres, this method is capable of the direct detection of the concentration of a specific DNA sequence. The label-free target DNA hybridizes with probe DNA of two kinds on the surface of the microspher...

Parathyroid hormone (PTH) and mechanical stress both stimulate bone formation but have opposite effects on bone resorption. PTH increased loading-induced bone formation in a rat model, suggesting that there is an interaction of these stimuli, possibly at the cellular level. To investigate whether PTH can modulate mechanotransduction by bone cells, we examined the effect of 10-9 M human PTH-(1-3...

This course is designed to provide students with an introduction to contemporary technologies and the implications for instructional practices that can serve as both a foundation and a process for continued growth and development in understanding teaching and learning. Throughout the course students will explore and critically examine how the World Wide Web and emerging digital technologies are...

Editor’s key points † This trial compared goal-directed haemodynamic therapy and conventional management in elderly patients undergoing femoral fracture surgery. † This is the largest single study in this patient group, but the trial was stopped early with no significant differences in primary outcomes. † The number of patients achieving haemodynamic goals was similar in both groups. † These re...

In this paper, the microfluidic size-separation technique pinched flow fractionation (PFF) is used to separate cancer cells from white blood cells (WBCs). The cells are separated at efficiencies above 90% for both cell types. Circulating tumor cells (CTCs) are found in the blood of cancer patients and can form new tumors. CTCs are rare cells in blood, but they are important for the understandin...

Objectives: Hip fractures in the elderly are common injuries that need timely surgical management. Since beginning of pandemic, patients with a proximal femoral fracture (PFF) experienced delay time to surgery. The primary aim this study was evaluate possible variation mortality PFF when comparing COVID-19 negative versus positive. Methods: This is multicentric and retrospective including 3232 ...

Abstract Parkinson’s Disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons and accumulation α-synuclein (α-Syn). Targeting JAK/STAT pathway to treat PD under investigation due its roles in inflammatory cytokine production activation immune cells. Striatal injection sonicated human α-Syn pre-formed fibrils (PFF) enhances cell infiltration, phosphorylation ...

It has been shown in Symanzik and Baker (1996a) that a particular subclass of Formalized Data Flow Diagrams (FDFD's) is Turing equivalent. We call this Turing equivalent subclass of FDFD's persistent flow-free Reduced Data Flow Diagrams (PFF--RDFD's). PFF--RDFD's do not contain persistent flows, reference only values whose types have finite domains, and have enabling conditions that contain no ...

Magnetic nanofiber has been widely applied in biomedical fields due to its distinctive size, morphology, and properties. We proposed a novel needleless electrospinning method to prepare magnetic nanofibers from the self-assembling "Taylor cones" of poly(vinyl pyrrolidone) (PVP)/Fe₃O₄ ferrofluid (PFF) under the coincident magnetic and electric fields. The results demonstrated that a static PFF R...