BACKGROUND Fatigue is a biological phenomenon that involves a feeling of extreme physical or mental tiredness that could potentially cause some severe chronic diseases. Recently, diet therapy has provided a new alternative to alleviate physical fatigue. In our previous study, addition of Cordyceps militaris (C. militaris) into an extruded product was shown to provide high nutrition and unique f...

logical changes including cell shrinkage, membrane bleebing, nuclear breakdown, and DNA fragmentation, and is essential for the maintenance of tissue homeostasis and the elimination of harmful cells. An apoptotic death stimulus activates caspases, the major executioners of this process, either directly or via the activation of the mitochondrial death program. The mitochondria-mediated pathway i...

Porcelain crabs, genera Petrolisthes and Pachycheles, are diverse and abundant members of the eastern Pacific near-shore decapod crustacean community. Morphology-based taxonomic analyses of these crabs have determined groupings of affiliated species, but phylogenetic relationships remain unknown. We used sequence data from the mitochondrial 16S rRNA gene of 46 species of eastern Pacific porcela...

We discovered a novel iflavirus from the transcriptome of the Bombyx mori pupa inoculated with the insect-pathogenic fungus Cordyceps militaris. The assembled iflavirus genome has 10,119 nucleotides, with a 3'-polyadenylated tail, and it encodes a polyprotein composed of 3,004 amino acids.

Polysaccharides isolated from fungus Cordyceps militaris display multi-biofunctions, such as immunostimulation, down-regulation of hyperlipidemia, and anti-cancer function. The occurrence obesity metabolic syndrome is related to the imbalance gut microbiota. In this study, effects C. its fractions on modifying in mice were evaluated. Mice fed a high-fat/high-sucrose diet (HFSD) for 14 weeks ind...

Cordycepin (3′-deoxyadenosine) exhibits antimicrobial, anticancer, antimetastatic, immunomodulatory and insecticidal effects, and is one of the most important bioactive anticancer agents found in Cordyceps species (summer grass-winter worm). However, due to the requirements of specific hosts and strict growth environments, Cordyceps militaris is very scarce in nature. Therefore, the production ...

In this study, the main bioactive compounds of the fruit bodies of Cordyceps militaris-such as adenosine, cordycepin, polysaccharides, mannitol, superoxide dismutase (SOD), and carotenoids-were cultivated on wheat and pupae, as well as sclerotium (the pupae portion) and sclerotium with fruiting bodies. The amounts of adenosine and polysaccharide in all the tested samples (except for the polysac...

This paper presents new records and noteworthy data on the following taxa in SE Europe adjacent regions: stonewort Chara intermedia, liverworts Fossombronia wondraczekii Pseudomoerckia blyttii, mosses Hamatocaulis vernicosus Hookeria lucens, monocots Gladiolus palustris, Neotinea tridentata, Orchis militaris dicots Cardamine serbica, waldsteinii, Hieracium kotschyanum Pilosella petraea are give...

Cordycepin (3?-deoxyadenosine) is a potent bioactive metabolite of the medicinal fungus Cordyceps militaris, which has been increasingly exploited to treat various chronic diseases in humans. However, current synthesis and purification procedures cordycepin are principally laborious complicated. This study provides simple protocol approach isolate purify from C. militaris by normal phase column...