BACKGROUND Few data exist in Latin America concerning the association between organophosphate (OP) urinary metabolites and the consumption of fruits and vegetables and other exposure risk variables in schoolchildren. METHODS We collected samples of urine from 190 Chilean children aged 6-12 years, fruits and vegetables, water and soil from schools and homes, and sociodemographic data through a...

Imidacloprid is a widely used pesticide in agriculture for controlling sucking insect pests, as a seed dressing, for soil treatment and as a foliar treatment in a variety of crops and orchards. Imidacloprid undergoes extensive metabolism in plants and forms monohydroxy imidacloprid, imidacloprid guanidine, imidacloprid olefin and a monoglucoside of 6-chloropicolyl alcohol. The majority of toxic...

In April 1995, the US Geological Survey began a study to determine the occurrence and temporal distribution of 49 pesticides and pesticide metabolites in air and rain samples from an urban and an agricultural sampling site in Mississippi. The study was a joint effort between the National Water-Quality Assessment and the Toxic Substances Programs and was part of a larger study examining the occu...

Body burdens from exposures to pesticides may be estimated from urinary analyses of pesticide parent/metabolite concentrations. Pesticide applicators and others are often exposed to numerous unrelated pesticides, either sequentially or simultaneously. Classically, body burdens of pesticides are analyzed using chemical/instrumental analysis (CIM) or enzyme immunoassays (EIAs). Both of these tech...

BACKGROUND A physiologically based pharmacokinetic (PBPK) model would make it possible to simulate the dynamics of chemical absorption, distribution, metabolism, and elimination (ADME) from different routes of exposures and, in theory, could be used to evaluate associations between exposures and biomarker measurements in blood or urine. OBJECTIVE We used a PBPK model to predict urinary excret...

Chlorpyrifos is a broad spectrum moderately toxic organophosphorous insecticide. It is widely used in agriculture for pest control and in households as a termicide. However, exposure to chlorpyrifos and its metabolites can affect the public health resulting from its long residual periods in soil and water. Thus, there is an essential need to develop sensitive method for the detection of chlorpy...

In April 1995, the U.S. Geological Survey began a study to determine the occurrence and temporal distribution of 49 pesticides and pesticide metabolites in air and rain samples from an urban and an agricultural sampling site in Mississippi. The study was a joint effort between the National WaterQuality Assessment and the Toxics Substances Programs and was part of a larger study examining the oc...

Little information has been published about pesticide exposures experienced by pregnant women. We measured six dialkyl phosphate (DAP) urinary metabolites of organophosphate (OP) pesticides in 600 pregnant, low-income women living in the Salinas Valley, California, an agricultural area. A total of 28% were employed as farm fieldworkers during pregnancy, and 81% had at least one household member...

This study was conducted to determine the effects of pesticide mixtures on degradation patterns of parent compounds as well as effects on soil microbial respiration. Bioavailability of residues to sensitive plant species was also determined. Soil for this study was obtained from a pesticide-contaminated area within an agrochemical dealer site. Degradation patterns were not affected by the prese...

Loose particles on impervious surfaces are an important carrier to transfer pesticides into residential runoff water and subsequently contribute to contamination of urban streams and estuaries by urban-use pesticides. However, data regarding levels of pesticide contamination in the runoff-transferable dusts are scarce and their runoff potential and toxicity impacts to urban watersheds still rem...