نتایج جستجو برای: peroxisome proliferator activated receptors
تعداد نتایج: 423823 فیلتر نتایج به سال:
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily. Their discovery in the 1990s provided insights into the cellular mechanisms involved in the control of energy homeostasis; the regulation of cell differentiation, proliferation, and apoptosis; and the modulation of important biological and patholo...
PURPOSE To assess the effects of Aleglitazar on hyperglycaemia-induced apoptosis. METHODS We incubated human cardiomyocytes, cardiomyocytes from cardiac-specific peroxisome proliferator-activated receptor-γ knockout or wild-type mice in normoglycaemic or hyperglycaemic conditions (glucose 25 mM). Cells were treated with different concentrations of Aleglitazar for 48 h. We measured viability, ...
Peroxisome Proliferator Activated Receptors Gamma (PPAR-ᵞ) is a nuclear transcription factor, which Protein receptors for insulin and have significant role in resistance Type 2 Diabetes mellitus addition to the of gene encoded differentiation Adipocyte development Adipose tissue. at present research has been detected substitution silent mutation C T exon 6 PPAR-ᵧ 111 women, including 73 obese w...
background: we determined the blood lipid-lowering effects ofeicosapentaenoic acid (epa) on hypertriglyceridemic subjects with leu162/val in exon 5 and g/c in intron7 polymorphism of peroxisome proliferator-activated receptor alpha (pparα)genotypes that, to our knowledge, have not been previously studied. methods: a total of170 hypertriglyceridemic subjects were enrolled and genotyped for ala...
Extrapulmonary pathology significantly impairs clinical outcome in chronic obstructive pulmonary disease (COPD). The peroxisome proliferator-activated receptors (PPARs) are implicated in the regulation of several hallmarks of systemic COPD pathology, including cachexia, decreased oxidative muscle metabolism, oxidative stress and systemic inflammation. Recently, expression of PPARs and related c...
Peroxisome proliferator-activated receptors-g (PPARg) are ligand-inducible transcription factors of the nuclear hormone receptor superfamily. We examined the ef
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید