نتایج جستجو برای: peroxin

تعداد نتایج: 177  

Journal: :Journal of cell science 2002
Cristina Guerra-Giraldez Luis Quijada Christine E Clayton

All kinetoplastids contain membrane-bound microbodies known as glycosomes, in which several metabolic pathways including part of glycolysis are compartmentalized. Peroxin 2 is essential for the import of many proteins into the microbodies of yeasts and mammals. The PEX2 gene of Trypanosoma brucei was identified and its expression was silenced by means of tetracycline-inducible RNA interference....

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Chris Williams Lukasz Opalinski Christiane Landgraf Joseph Costello Michael Schrader Arjen M Krikken Kèvin Knoops Anita M Kram Rudolf Volkmer Ida J van der Klei

The initial phase of peroxisomal fission requires the peroxisomal membrane protein Peroxin 11 (Pex11p), which remodels the membrane, resulting in organelle elongation. Here, we identify an additional function for Pex11p, demonstrating that Pex11p also plays a crucial role in the final step of peroxisomal fission: dynamin-like protein (DLP)-mediated membrane scission. First, we demonstrate that ...

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