نتایج جستجو برای: perivascular infiltration
تعداد نتایج: 58470 فیلتر نتایج به سال:
The blood-brain barrier regulates the flow of ions, chemicals, and cells by acting as a conduit between blood cerebral tissue. Additionally, it shields brain against pathogen invasion immune cell infiltration. It is composed endothelial cells, pericytes, astrocytic end feet, perivascular macrophages, microglial which help in maintaining its integrity. There are various signaling pathways that a...
cerebral coenurosis is the intermediary larval stage of taenia multiceps , which affects intermediate hosts, particularly sheep and goats. in this report, gross and microscopic features of three scarce natural coenurosis cases, a oneyear-old ram and two lambs of 7 month old from a flock are explained. atnecropsy, numerous small cysts measuring 5 to 10 mm in diameter were observed on both cerebr...
Background Angiogenesis and immune cell infiltration are key features of gliomas and their manipulation of the microenvironment, but their prognostic significance remains indeterminate. We evaluate the interconnection between tumor-infiltrating lymphocyte (TIL) and tumor blood-vasculatures in the context of glioma progression. Methods Paired tumor tissues of 44 patients from three tumor-recur...
BACKGROUND Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma (SCC) are debated. The purpose of this study was to investigate the association of prognostic factors with oncologic outcomes. METHODS Patients with oral cavity and oropharyngeal SCC treated from 1997 to 2012 were included in this retrospective cohort study. Associations of prognostic factors with locoregio...
Cerebral magnetic resonance elastography (MRE) measures the viscoelastic properties of brain tissues in vivo. It was recently shown that brain viscoelasticity is reduced in patients with multiple sclerosis (MS), highlighting the potential of cerebral MRE to detect tissue pathology during neuroinflammation. To further investigate the relationship between inflammation and brain viscoelasticity, w...
OBJECTIVE Despite substantial progress in recent years, graft survival beyond the first year still requires improvement. Since modern immunosuppression addresses mainly T-cell activation and proliferation, we studied macrophage infiltration into the allografts of 103 kidney transplant recipients during acute antibody and T-cell mediated rejection. Macrophage infiltration was correlated with bot...
The human testes in cases of malignant hematopoietic tumors, especially of leukemia, were histologically examined to characterize the mode of leukemic infiltration in comparison with that of malignant lymphoma. Materials were obtained from 56 autopsy cases, composed of 47 of leukemia, 7 of reticulum cell sarcoma and 2 of lymphosarcoma. Leukemic infiltration was confirmed in 43 (19%) of all leuk...
A skeletal muscle involvement associated with skin, renal and liver pathology has been described in patients with essential mixed cryoglobulinemia. In some cases the muscle atrophy was consequence of a peripheral neuropathy but in such patients the muscle pathology has not been defined. Skin and skeletal muscle biopsies were performed in 6 patients with type II essential mixed cryoglobylinemia....
BACKGROUND Omega-3 polyunsaturated fatty acids (ω3 PUFAs) suppress inflammation through activation of free fatty acid receptor 4 (FFAR4), but this pathway has not been explored in the context of cardiovascular disease. We aimed to elucidate the involvement of FFAR4 activation by ω3 PUFAs in the process of vascular inflammation and neointimal hyperplasia in mice. METHODS AND RESULTS We used mi...
The virulence and immunogenicity (protectivity) of an attenuated live strain of Paeteurella pestis, EV, were examined in mice. When injected subcutaneously at a dose of 106 bacilli, the organisms survived at the injection site for as long as one week though the population decreased gradually. A small number of EV was recovered from the spleen, liver and kidneys from the second to the fifth days...
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