N thi's paper we describe an econometric model of the American tobacco industry for the period 1949 through 1966. The model contains 19 equations and is divided into three major blocks (1) leaf production, (2) leaf price, and (3) cigarettes. The objective is to explain the behavior of the tobacco industry over an 18-year period. Ultimately, we hope to use the model to perform policy simulation ...

Emerging evidence indicates that the aryl hydrocarbon receptor (AhR) plays a crucial role in normal physiologic homeostasis. Additionally, aberrant AhR signaling leads to several pathologic states in the lung and liver. Activation of AhR transcriptionally induces phase I (CYP1A) detoxifying enzymes. Although the effects of the classic AhR ligands such as 3-methylcholanthrene and dioxins on phas...

This study aimed to investigate the impact of methylxanthine abstinence (MA) periods on CYP1A2 activity in individuals with varying levels of caffeine consumption through development of a population pharmacokinetic model of caffeine and its major metabolite paraxanthine. This study developed and evaluated a mixed-effects pharmacokinetic model for caffeine and paraxanthine concentration-time dat...

Emerging evidence indicates that the aryl hydrocarbon receptor (AhR) plays a crucial role in normal physiologic homeostasis. Additionally, aberrant AhR signaling leads to several pathologic states in the lung and liver. Activation of AhR transcriptionally induces phase I (CYP1A) detoxifying enzymes. Although the effects of the classic AhR ligands such as 3-methylcholanthrene and dioxins on phas...

(i) Westminster Hospital, 1716-1966, by J. G. HUMBLE AND P. HANSELL, London, Pitman Medical Publishing Co., 1966, pp. x, 134, illus., 21s. (ii) Geschichte des Hospitals, Bd. 1: Westdeutschland von den Anfdngen bis 1850, by D. JETFER (Sudhoffs Archiv, Beiheft 5), Wiesbaden, Franz Steiner Verlag, 1966, pp. viii, 270, 104 illus., DM. 66 or 74. These two books could hardly be more different. Dr. Hu...

The development of MT system design is described in four periods: the early experimental period (1946-54), the period of large-scale research on 'direct translation' systems (1956-66), the period after the ALPAC report in which the 'interlingual' and 'transfer' approaches were developed (1966-75), and the current period in which interactive systems and 'artificial intelligence' approaches have ...

The primary purpose of the study was determination spatial day-to-day variability extreme air temperatures in Poland and dependency large temperature changes on atmospheric circulation accordance with Grosswetterlagen (GWL) classification. goal achieved based data from 1966 to 2015, made available by Institute Meteorology Water Management—National Research Institute. Day-to-day maximum minimum ...

Building a new socialist culture: Mobile projection teams as propaganda tool in People’s Republic of China 1949–1966 After the founding China, Chinese Communist Party (CCP) embarked on groundbreaking project: creation art for “workers, peasants and soldiers.” In this great endeavour designed to shape “new man,” film proved be one most effective tools so-called mobile (MPT) crisscrossing country...