OBJECTIVES/HYPOTHESIS To identify histopathologic features associated with poor correlation of frozen and permanent pathology margins following wide local excision for advanced cutaneous squamous cell carcinomas of the head and neck. STUDY DESIGN Retrospective review. METHODS A retrospective review of patients undergoing excision of advanced head and neck squamous cell carcinomas between th...

introduction: squamous cell carcinoma (scc) is the most common head and neck malignancy. to decrease the side effects of treatment and mortality from disease relapse, careful staging for the proper treatment plan is necessary. the main purpose of this prospective study is to compare the diagnostic value of computed tomography (ct) and magnetic resonance im-aging (mri) in oral scc and its lymph ...

BACKGROUND Perineural invasion is a common path for cholangiocarcinoma (CCA) metastasis, and it is highly correlated with postoperative recurrence and poor prognosis. It is often an early event in a disease that is commonly diagnosed in advanced stages, and thus it could offer a timely therapeutic and diagnostic target if better understood. This article systematically reviews the progress of CC...

introduction rhino-orbito-cerebral mucormycosis is a progressive angioinvasive fungal disorder which almost always complicates immunocompromised patients. case presentation we described a case of fulminant rhino-orbito-cerebral mucormycosis in a 65-year-old woman, who presented with progressive neurological deficits due to involvement of orbital apex and the central nervous system by local inva...

BACKGROUND The 5-year survival rate of the patients with stage I colorectal cancer is about 90%; therefore, adjuvant therapy has not been recommended after radical resection; however, about 16-26% of T2N0M0 patients will be dead at 5 years despite radical curative resection. It indicated that there is a defined group of patients who are at high risk for relapse or metastasis despite radical ope...