We describe a case of severe perianal Crohn’s disease masquerading as perianal warts in a non-sexually active adolescent girl presenting to a genitourinary medicine clinic. Perianal Crohn’s disease should always be suspected in children and adolescents presenting with perianal skin manifestations to any healthcare settings in order to avoid delay in diagnosis and treatment of this chronic disab...

BACKGROUND Idiopathic perianal pruritus is a poorly managed condition. Topical corticosteroids are effective in idiopathic perianal pruritus, but they may cause some side effects. In this study, the effectiveness of topical steroids were compared with perianal cleansers in the treatment of idiopathic perianal pruritus. PATIENTS AND METHODS Seventy two patients with the complaint of perianal p...

The skins of mice, rats, rabbits, sheep, guinea pigs, and dogs were cultured for Propionibacterium acnes. Only the sebaceous regions (perianal gland) of guinea pigs harbored a significant P. acnes population. Analysis of the lipid from this region revealed a significant percentage of triglycerides, compounds lacking in the sebum of the other animals.

Background: Perianal fistula is a complicated disorder and most difficult to manage. New treatment methods would help surgeons to achieve a better outcome in patients with perianal fistula. Human amniotic membrane (HAM) has positive effects on wound healing in several conditions. The present study aimed to further determine the effect of HAM on wound healing of perianal fistula in rabbits.Metho...

Rationale: Reports on perianal atypical leiomyoma, a perianal tumor, are rare. We confirmed a perianal atypical leiomyoma by its clinical presentation, magnetic resonance imaging findings, and immunohistochemistry. Patientconcerns:A 28-year-old female with a perianal mass found more than 4 years ago. The 5cm_4cm_4cm sized mass was located on the left side of the anus and vagina; The magnetic re...

Median raphe cysts (MRC) are uncommon, benign congenital lesions that may present anywhere in the midline between the urinary meatus and the anus, with the shaft of the penis and the glans penis being the most common sites. We report a 52-year-old man with median raphe cyst unusually located in perianal region and treated by surgical excision.

Fournier's gangrene is a usually polymicrobial, necrotizing, life-threatening fasciitis of the perineal, genital and perianal region. It is a fulminant disease which can rapidly spread to the abdominal wall and cause a high mortality. It is important to diagnose the disease process as early as possible as when the tyreatment is delayed mortality rate is directly increased.

BACKGROUND The antibody Ki-67 is a reliable and easy tool to accurately assess the growth fraction of neoplasms in humans and animals, and it has been used to predict the clinical outcome. Therefore, the aim of the present study was to investigate the immunohistochemical expression pattern of Ki-67 in normal and neoplastic perianal glands of dogs to evaluate the possible use of this proliferati...