background: artemisia dracunculus l. belongs to the anthemideae tribe of asteraceae family. this plant has been used in traditional folk medicine. also, it's anti-bacterial, anti-fungal, antioxidant, anti-inflammatory and hepatoprotective activity has been proved. objective: the purpose of this study was to evaluate the antioxidant activity of leaves and inflorescence of a. dracunculus and...

of isotopically labelled vitamin D metabolites by HPLC. Journal of Chromatography 303: 229}233. Kaspersen FM, van Acquoy J, van de Laar GLM, Wagenaars GN and Funke CW (1984) Deuterium isotope effects in mianserin. Recueil Travaux Chimique de Pay-Bas 103: 32}36. Klein PD (1966) Occurence and signiRcance of isotope fractionation during analytical separation of large molecules. Advances in Chromat...

Introduction Drug manufacturing control requires high level and intensive analytical and chemical support of all stages to ensure the drug's quality and safety. The pharmacopeia constitutes a collection of recommended procedures for analysis and specifications for the determination of pharmaceutical substances, excipients, and dosage forms that is intended to serve as source material for refere...

Simultaneous quantitative analysis of 10 indole compounds, including indole-3-acetic acid (IAA, one of the most important naturally occurring auxins) and some of its metabolites, by high performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) after solid-phase extraction (SPE) was reported for the first time. The analysis was carried out using a reverse phas...

High-performance liquid chromatography (HPLC) is the most versatile of the chromatographic techniques because it is applicable to a wide variety of analytes. Unfortunately, liquid mobile phases have relatively low diffusivities. A novel approach is presented for increasing the diffusivity of a liquid mobile phase. The method advocated in this study is the first process that has been described b...

Nicorandil is a potent drug with a dual mechanism of action which results in its wide application in treating angina patients. Since the literature review showed no single preparative method for isolation and liquid chromatography-mass spectrometry (LC-MS) compatible [high-performance liquid chromatography (HPLC) or ultra performance liquid chromatography (UPLC)] method for identification for t...

Isomangiferin was isolated from Cyclopia subternata using a multi-step process including extraction, liquid-liquid partitioning, high-speed counter-current chromatography (HSCCC) and semi-preparative reversed-phase high-performance liquid chromatography (HPLC). Enrichment of phenolic compounds in a methanol extract of C. subternata leaves was conducted using liquid-liquid partitioning with ethy...