Purpose. To compare the higher-order aberrations (HOAs) due to the anterior and posterior corneal surfaces in patients that underwent either Descemet-stripping-automated-endothelial-keratoplasty (DSAEK) or penetrating keratoplasty (PK) for endothelial dysfunction and age-matched controls. Methods. This retrospective, observational, case series included 28 patients after PK, 30 patients after DS...

PURPOSE A single-center, cross-sectional study was designed to assess and compare objective and subjective quality of vision of patients intervened with penetrating keratoplasty (PK), deep anterior lamellar keratoplasty (DALK) and Descemet membrane endothelial keratoplasty (DMEK). METHODS Forty-six patients previously intervened with PK (22 eyes), DALK (7 eyes) and DMEK (17 eyes) were recruit...

Conventional corneal transplantation, in the form of penetrating keratoplasty (PK), involves full-thickness replacement of the cornea, and is a highly successful procedure. However, the cornea is anatomically a multi-layered structure. Pathology may only affect individual layers of the cornea, hence selective lamellar surgical replacement of only the diseased corneal layers whilst retaining una...

Purpose: Glaucoma following penetrating keratoplasty (PK) continues to be a serious problem that may ultimately become sight threatening. Knowledge of the risk factors for development of glaucoma following PK, such as preexisting glaucoma, pseudophakia, aphakia, and previous PK, can limit the occurrence and improve the outcome of the keratoplasty. The management of postkeratoplasty (Post-PK) gl...

PURPOSE The purpose of this report is to highlight the potential risk of noncontact tonometry after routine uncomplicated penetrating keratoplasty (PK). CASE REPORT After uncomplicated PK for keratoconus, routine noncontact tonometry was performed on the second postoperative day. In spite of the adequately closed wound and the tight suture, temporary wound dehiscence occurred, and two-thirds ...

PURPOSE The secretion of transforming growth factor-beta2 (TGF-beta2) into the aqueous humor was identified to be important for the maintenance of the immunological privilege in the anterior chamber of the eye. Therefore, prognosis of penetrating corneal grafts might depend on intraocular levels of TGF-beta2. In this study, we determined active TGF-beta2 levels in eyes with pathological corneas...

PURPOSE Penetrating keratoplasty and epikeratoplasty have been utilized in the surgical treatment of keratoconus. Comparison of the relative efficacy of each procedure in achieving visual outcomes has not been achieved due to limited numbers of cases and follow-up in previous series. METHODS All patients who underwent either penetrating keratoplasty or epikeratoplasty for keratoconus between ...

PURPOSE To determine if the use of combined HLA matched limbal stem cells allograft with amniotic membrane transplantation (AMT) is a safe and effective prophylactic surgical procedure to prevent corneal graft after penetrating keratoplasty (PK). METHODS We report the case of a 17 years old patient with a history of congenital glaucoma, trabeculectomy and multiple corneal graft rejections, pr...

PURPOSE The aim of the study was to evaluate the various donor and recipient factors associated with short-term prevalence of surface epithelial keratopathy after optical penetrating keratoplasty (OPK). METHODS Preoperative and postoperative data of 91 eyes of 91 patients were reviewed retrospectively who had undergone OPK from March 2013 to February 2016. Donor and recipient data were analyz...

PURPOSE To estimate cure rate following graft rejection in bilateral corneal transplants in Iranian patients with keratoconus and to determine risk factors associated with rejection. METHODS In this retrospective study, data were compiled from records of patients who had undergone bilateral penetrating keratoplasty (PK) for keratoconus between 1988 and 2007. In order to estimate cure rate in ...