abstract: peganum harmala l. (zygophylaceae) has been used in a variety of practical applications in medical science. our objective in the current study was to determine the effects of the seed extract on herpes simplex virus type 1 (hsv-1) replication in vero cells. different concentrations (100, 500, 571, 667, 800 and 1000 µg/ml) of the extract were examined. experiments were carried out usin...

conclusions according to the current study results, it may be concluded that ethanol extract of p. harmala is efficient in the treatment of cutaneous leishmaniasis, and the efficiency is comparable with that of glucantime. results the results showed that ethanol extract of p. harmala had good therapeutic efficacy in treatment of lesions in mice (p < 0.05), and the efficacy was significant in th...

Parasites of the genus Leishmania are transmitted by sandflies that ingest the parasite in the amastigote stage resident within macrophages, then inoculate the promastigote stage into other hosts. Peganum harmala, or Syrian Rue, has pharmacologically active compounds including several alkaloids with antiprotozoal properties, which are found especially in the seeds and the roots. In this researc...

the effects of hydroalcoholic extract of peganum harmala seeds (eps) on spontaneous rhythmic contractions of isolated rat uterine was investigated in this study. eps was tested on the isolated uterus and endometrium free (i.e. stripped myometrium) preparations. eps was found to exhibit significant spontaneous contractions of the uterus and stripped myometrium relative to the solvent control. af...