Preliminary studies on use of the synthetic prostaglandin, fenprostalene, as an abortifacient had indicated that maximum effectiveness was dependent upon slow delivery. Because both route of administration and formulation control delivery rates, the influences of intramuscular (im) vs subcutaneous (sc) injections, and aqueous acetate buffer (AAB) vs polyethylene glycol-400 (PEG) vehicles on the...

Polyethylene glycol (PEG) used as a brightening and stabilization agent at the concentration of 30 mg dm(-3) is a major organic additive in the copper electroplating solution. Activated carbon, Calgon Filtrasob 400, is used as the adsorbent to remove the PEG from the used electroplating solution in order to broaden the appeal of recycling it. The equilibrium of adsorption is attained within 14 ...

Due to unique applications of palladium nanoparticles, synthesis of these nanoparticles by a simple and low cost method is very important. In this work, Pd nanoparticles were synthesized with narrow size distribution by loading metal salt (Pd(OAc)2 ) into the polymeric matrix (PEG) as reducing agent and stabilizer. Also, the effect of metal salt concentration and PEG molecular weight on the con...

Poly(ethylene glycol) (PEG) hydrogels are widely used to deliver therapeutic biomolecules, due to high hydrophilicity, tunable physicochemical properties, and anti-fouling properties. Although different hydrogel crosslinking mechanisms are known to result in distinct network structures, it is still unknown how these various mechanisms influence biomolecule release. Here we compared the effects ...

Growing applications of phenylalanine dehydrogenase (PheDH) enzyme in the medical and pharmaceutical industries encourages researchers to seek simple, fast and economical alternative purification methods. With goal of finding a new technique, the extraction and purification of recombinant Bacillus badius PheDH in polyethylene glycol 6000 (PEG-6000) and ammonium sulfate aqueous two-phase systems...

Noncontact manipulation of nano/micromaterials presents a great challenge in fields ranging from biotechnology to nanotechnology. In this study we developed a new strategy for the manipulation of molecules and cells based on diffusiophoresis driven by a concentration gradient of a polymer solute. By using laser focusing in a microfluidic device, we created a sharp concentration gradient of poly...

BACKGROUND Intravenous injection of lycobetaine was found to show significant cytotoxic activity against (inter alia) Lewis lung carcinoma, but its therapeutic use is largely limited due to an extremely short half-life in blood. This study aimed at developing a novel lipid nanocarrier-based formulation for lycobetaine delivery. The formulation is feasible for scale-up production, exhibiting goo...

The results are summarized in Table 1. The baseline absorbance of untreated plasma samples was significantly higher (0.106 6 0.076) than that of plasma samples treated with PEG (0.007 6 0.003; t 5 5.95; P ,0.001). There were no significant differences between the recovered ICG concentrations and the expected values at any of the four dye concentrations. Zweens and Frankena (4 ) demonstrated tha...