Background. Lichen Planus is a chronic mucocutaneous disease of immunological basis and unknown etiology. women with oral lichen planus may have concomitant manifestations in vulvovaginal areas. Objective. To determine the frequency and risk factors of genital involvement in a group of Iranian women affected by oral lichen planus. Methods. Thirty-six women with clinical and histopathological di...

UNLABELLED Histopathological diagnosis of oral lichen planus is not easy since some cases of epithelial dysplasia may present traits which are very similar to those from lichen planus. AIM to compare cell alterations which suggest malignancy present in oral lichen planus with those from epithelial dysplasia. MATERIAL AND METHODS histological cross-sections of oral lichen planus and dysplasi...

BACKGROUND Multiple intrinsic and extrinsic soft tissue structures that apply forces and support the medial longitudinal arch have been implicated in pes planus. These structures have common functions but their interaction in pes planus is not fully understood. The aim of this study was to compare the cross-sectional area (CSA) and thickness of the intrinsic and extrinsic foot muscles and plant...

Lichen planus is a dermatologic disease of unknown etiology characterized by keratotic plaques on the skin. Many patients also harbor white lesions of the oral mucosa. The literature contains numerous reports of lichen planus-like lesions evolving in conjunction with the administration of a variety of pharmacologic agents. It is difficult, if not impossible, to distinguish such lesions from one...

Background: Lichen planus is a skin disease that rarely involves mucus membrane. Case: In this study, we introduced a rare case of lichen planus of the right vocal cord in a 51- year -old male presented with hoarseness. The lesion started two years ago and the hoarseness became progressive. There were not any lesions found in his buccal mucosa and skin. The biopsy of the lesion showed lichen...

INTRODUCTION Up to 30% of squamous cell carcinomas of the penis arise from a lichen sclerosus, but very few reports in which lichen planus was the preexisting lesion have been published. We report a male with verrucous carcinoma of penis that developed in an area of lichen planus. CLINICAL CASE A 53-year-old male presented with an exophytic tumor on the glans penis that had been present for a...

Lichen planus is a fairly distinctive, chronic, immunologically mediated mucocutaneous disease, of uncertain etiology that was first described as a disease of the skin that can also affect mucosal surfaces, including those that line the oral cavity. The prevalence of LP in the general population is of the order of 0.9 to 1.2%. It is stated that approximately 40% of lesions occur on both oral an...

Introduction: Malondialdehyde (MDA) is a useful determinant to show high level of lipid peroxidation which lead to impaired cell function. Previous studies have mentioned there is a relationship between high oxidative stress and low anti-oxidant activity in patients with oral lichen planus. The aim of this study was to evaluate serum level of Malondialdehyde as an indicator of oxidative stress ...

Lichen planus is a mucocutaneous disease, predominantly affecting the middle-aged individuals and may be associated with a plethora of signs and symptoms related to the skin, scalp, nails and mucous membranes. The definitive etiology of lichen planus is not yet known and no therapeutic modality has yet been universally accepted. Lichen planus in pediatric patients is a rare phenomenon and its p...

Oral lichen planus is a chronic non-infectious mucosal inflammatory disease caused by an imbalance between reactive oxygen species homeostasis and antioxidant defense systems. Notably, excessive oxidative stress products result in related autoimmune reactions. Further, it activates signaling pathways to the development of oral planus, as evidenced detection damage deoxyribonucleic acid, protein...