The occurrence of protein C inhibitor (PCI) in human platelets and megakaryocytes was analyzed. As judged from enzymelinked immunosorbent assays (ELISAs), PCI was present in platelets at a concentration of 160 ng/2 3 109 cells. Its specific activity was 5 times higher than that of plasma PCI. Consistently, mainly the 57-kD form (active PCI) and some high molecular weight (Mr) forms, but no band...

BACKGROUND Optimal reperfusion strategy in ST-elevation myocardial infarction is controversial. Failure of fibrinolytic therapy is related to limited efficacy, high reocclusion rates, reinfarction, and systemic bleeding complications. Data on the impact of percutaneous coronary intervention (PCI) after fibrinolysis are conflicting. The Southwest German Interventional Study in Acute Myocardial I...

OBJECTIVE To investigate whether common risk stratification models in cardiac surgery predict perioperative outcome of coronary artery bypass grafting (CABG) in patients with previous percutaneous coronary interventions (PCIs). METHODS We retrospectively analyzed the perioperative mortality and morbidity of 367 patients with prior elective PCI versus 2361 patients without prior PCI, who under...

bacground: evidence from several lines of investigations suggests that toll-like receptor 4 (tlr4) is involved in atherosclerosis as a bridge between innate and acquired immunity. percutaneous coronary intervention (pci) can trigger inflammation through activation of human tlr4 (htlr4) on monocytes. hydrocortisone as an anti-inflammatory and immuno-suppressant agent has multiple mechanisms of a...

D uring the past decade, advances in device technology (eg, drug-eluting stents), development of safer antico-agulants (eg, bivalirudin), and refinement in procedural techniques have led to a dramatic improvement in the effectiveness and safety of percutaneous coronary intervention (PCI), despite increasing clinical and anatomic complexity of treated patients. 1 As safety and effectiveness have...

We developed a PCI interface for GRAPE systems. GRAPE(GRAvity piPE) is a special-purpose computer for gravitational N -body simulations. A GRAPE system consists of GRAPE processor boards and a host computer. GRAPE processors perform the calculation of gravitational forces between particles. The host computer performs the rest of calculations. The newest of GRAPE machines, the GRAPE-4, achieved ...

BACKGROUND The optimal treatment of unprotected left main (UPLM) with either PCI or CABG remains uncertain. AIM The purpose of this study was to determine the comparative safety and efficacy of PCI versus CABG in patients with UPLM disease. METHODS Search of BioMedCentral, CENTRAL, mRCT, PubMed, major cardiological congresses proceedings and references cross-check (updated November 2016). O...