OBJECTIVE Lead (Pb) poisoning remains a common disease among children despite successful public health efforts that have reduced its prevalence. Treatment options for children with blood Pb levels (BPbs) <45 micro g/dL are limited because chelation therapy is generally not indicated. Calcium (Ca) and Pb interactions are well documented. Competition for binding to Ca-binding proteins may underli...

As a top predator, the white-tailed eagle (Haliaeetus albicilla) may serve as a good indicator species, providing information about the bioavailability of contaminants and their transfer within the food chain. In this study, we aimed to determine the common sources of origin of 17 metals and other elements in the liver of white-tailed eagles, and to compare the variations in their hepatic conce...

Introduction The biotransformation of polychlorinated biphenyls, world-wide environmental pollutants, is initiated mainly by an oxygenation of aromatic ring catalyzed by liver cyochrome P450(P450) [1]. A series of our studies using some tetrachlorobiphenyls (TCBs), major components of Kanechlor 400 caused Yusho poisoning in Japan in 1968, demonstrated that the hydroxylating ability of liver mic...

Parameters indicative of absorption and biological effect in new lead exposure: a prospective study. Determinations have been made of the blood and urinary lead concentrations (Pb-B, Pb-U), haemoglobin concentrations (Hb), packed blood cell volumes (Hcr), urinary 8-aminolevulinic acid (ALA-U) and coproporphyrin concentrations (CP-U), as well as erythrocyte 8-aminolevulinic acid dehydratase acti...

Lead contamination is a serious threat to human health and the environment. 2] Lead poisoning is still one of the most common environmentally caused diseases in the world today. Lead levels are typically measured by using atomic absorption spectroscopy or other related instrumental methods. Probes that can provide rapid, on-site evaluation of the lead content of a sample are very valuable for a...

Lead poisoning is known to cause myelin defects. Galactolipids are the major lipid components of myelin and myelin-competent oligodendrocytes. The present study examines the cellular activity of enzymes involved in the galactolipid pathway, tissue concentrations of galactolipids, and the cellular activity of 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNPase) in rat pups exposed to lead in ute...

background:the use of herbal or medicinal plants in various forms has been popular for thousands of years. it is estimated that about 70–80% of the world’s population relies on alternative medicine, mainly of herbal origin. however, due to the nature and sources of these plants, they are sometimes contaminated with toxic heavy metals, which pose serious health risks to consumers. herbal formula...

Abstract The concentrations of heavy metals (Pb, As, Cr, Cu, Cd and Fe) were determined in the gills, liver muscles thirty-five fishes, water sediment samples from Aba River using atomic absorption spectrophotometer. Heavy metal varied markedly among fish species organs. Results revealed that Pb, Fe had maximum concentration levels 0.63±0.01, 0.81±0.01 16.91 ± 0.20 mg/kg Chrysichthys nigrodigit...

Lead (Pb) accumulation in parts of maize plant as a possible route for Pb poisoning was investigated. Experimental design adopted 3 factorial combination (4 x 1 1). Prior to planting seeds, soil sample analyzed its physicochemical properties. At maturity, crop and the plants were harvested their contents. TF, BCF BAF well determined. Physicochemical properties’ results revealed that pH 6.75, Ec...