Conjugated linoleic acid (CLA), a naturally occurring peroxisome proliferator-activated receptor gamma (PPAR gamma) ligand, exhibits proapoptotic, immunomodulatory, and anticancer properties. In this study, we examined the biological effects of CLA administration in the MRL/MpJ-Fas(lpr) mouse, an animal model of systemic lupus erythematosus (SLE). We found that CLA exerted apparently opposed ac...

Abstract A dwarf sperm whale Kogia sima stranded alive along the Central Pacific Coast of Costa Rica. The whale, handled by tourists and local inhabitants, was weak, had buoyancy difficulties, eventually aborted died, showing severe necrotizing placentitis other pathological signs. Both mother fetus antibodies against Brucella lipopolysaccharide. organisms were isolated from various tissues bot...

A recent necropsy study has shown that 80% of patients with the Wernicke-Korsakoff syndrome were not diagnosed as such during life. Review of the clinical signs of these cases revealed that only 16% had the classical clinical triad and 19% had no documented clinical signs. The incidence of clinical signs in this and other retrospective pathological studies is very different from that of prospec...

This study evaluated the ameliorative effects of Antox® and Bactofort® on clinico-pathological changes in ISA Brown chicks inoculated with a very virulent infectious bursal disease virus (vvIBDV). Two hundred (200) day-old were randomly assigned into four groups (A to D) 50 birds each. Groups A, B administered Antox®, Bactofort®, respectively from 42 days age, vvIBDV at 28 age. C, D served as p...

Gastro-esophageal reflux (GER) is a physiological phenomenon occurring in every individual. Gastro-esophageal reflux Disease (GERD) is a pathological condition where the reflux into the esophagus causes local changes and aspiration of the gastric contents in to the lungs can cause serious, even life threatening conditions. GERD is common but under-diagnosed condition in children. There are fund...

Chronic intestinal pseudo-obstruction (CIP) represents a particularly difficult clinical challenge. It is a rare and highly morbid syndrome characterised by impaired gastrointestinal propulsion together with symptoms and signs of bowel obstruction in the absence of any lesions occluding the gut lumen. CIP can be classified as either "secondary" to a wide array of recognised pathological conditi...

Sarcoidosis is a multisystem disease of unknown cause and with a worldwide distribution. Involvement of the central nervous system occurs in a relatively small number of patients with sarcoidosis. Isolated neurosarcoidosis without signs of systemic disease however is a rare. In this report, we present an unusual case of neurosarcoidosis with intra cranial mass mimicking radiologically a glioma....

The dental surgeon can feel inadequate when confronted with a rare disease: (a) difficult diagnosis, (b) therapeutic complexity, (c) and questioning by the parents, are three major obstacles that we have to overcome in order to carry out our therapy. Even if the field of genetics has made major advances during the last few years, it is clinical knowledge, above all, that leads us to a diagnosis...